KOMATE Registry: Korean Multicenter Angioplasty Team

Primary outcomes

1. Target lesion revascularization

   Time frame: Up to 20 years

   Defined as any repeat percutaneous intervention of the target lesion or bypass surgery of the target vessel performed for restenosis or other complication of the target lesion. All TLRs should be classified prospectively as clinically indicated or not clinically indicated by the investigator prior to repeat angiography. Clinically indicated revascularization: A revascularization is considered clinically indicated if angiography at followup shows a percent diameter stenosis ≥ 50% and if one of the following occurs:

   • A positive history of recurrent angina pectoris, presumably related to the target vessel;
   • Objective signs of ischemia at rest (ECG changes) or during exercise test (or equivalent), presumably related to the target vessel;
   • Abnormal results of any invasive functional diagnostic test (eg, Doppler flow velocity reserve, fractional flow reserve);
   • A TLR or TVR with a diameter stenosis ≥ 70% even in the absence of the above-mentioned ischemic signs or symptoms.

2. Target vessel revascularization

   Time frame: Up to 20 years

   Defined as any repeat percutaneous intervention of the target lesion or bypass surgery of the target vessel performed for restenosis or other complication of the target lesion. All TLRs should be classified prospectively as clinically indicated or not clinically indicated by the investigator prior to repeat angiography. Clinically indicated revascularization: A revascularization is considered clinically indicated if angiography at followup shows a percent diameter stenosis ≥ 50% and if one of the following occurs:

   • A positive history of recurrent angina pectoris, presumably related to the target vessel;
   • Objective signs of ischemia at rest (ECG changes) or during exercise test (or equivalent), presumably related to the target vessel;
   • Abnormal results of any invasive functional diagnostic test (eg, Doppler flow velocity reserve, fractional flow reserve);
   • A TLR or TVR with a diameter stenosis ≥ 70% even in the absence of the above-mentioned ischemic signs or symptoms.

3. Stent thrombosis

   Time frame: Up to 20 years

   Stent thrombosis is defined and discussed by the Academic Research Consortium

4. Myocardial infarction

   Time frame: Up to 20 years

   Myocardial Infarction Classification and Criteria for Diagnosis is defined by the Academic Research Consortium

5. Death

   Time frame: Up to 20 years

   All death will be recorded and their reason also be recorded. Also, cardiac death is defined as death due to myocardial infarction, cardiac perforation, tamponade, arrhythmia or any cardiac cause.

6. Non-target vessel revascularization

   Time frame: Up to 20 years

   Any revascularization of target-vessel revascularization will be collected.

7. Cerebrovascular accident

   Time frame: Up to 20 years

   Sudden onset of vertigo, numbness, aphasia, dysarthria or central neurologic deficit secondary to vascular lesions of the brain such as hemorrhage, embolism, thrombosis, or rupturing aneurysm, that persist for > 72 hours.

8. Major bleeding

   Time frame: Up to 20 years

   Any bleeding event will be collected with following description; the amount of hemoglobin drop or transfusion, the site of bleeding, any further treatment for the bleeding.

9. Cardiovascular readmission

   Time frame: Up to 20 years

   Any readmission due to cardiovascular adverse event will be collected.