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Completed

NCT Number: NCT06678009

Isokinetic Training Combined with Blood Flow Restriction on Muscle Strength and Endurance

Evidence regarding the effectiveness of blood flow restriction during isokinetic exercises is insufficient. When the literature is reviewed, it is seen that there are very few studies investigating the effect of isokinetic training program with blood flow restriction on muscle strength and endurance in healthy athletes. In line with this information, the aim of this study was to investigate the effect of an 8-week isokinetic training program combined with blood flow restriction on knee flexor and extensor maximal muscle strength and endurance in runners.

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Key information

Age range

20 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Health Sciences, Gulhane Faculty of Medicine, Ankara, Turkey (Türkiye)

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About this study

The purpose of this study is to investigate the effect of lower extremity isokinetic training combined with blood flow restriction (BFR) on knee flexor and extensor muscle strength and endurance in runners. A total of 42 runners were randomly assigned to either the isokinetic training group with blood flow restriction (BFR Group; n= 21) or the isokinetic training group without blood flow restriction (Control Group; n= 21). For the BFR, the occlusion pressure was set to 80% of arterial occlusion pressure as determined. The isokinetic training protocol for the knee flexor and extensor muscles consisted of 3 sets of 10 repetitions in 60°/sec and 3 sets of 30 repetitions in 180°/sec for 8 weeks, 2 times per week for 16 sessions. The muscle strength and endurance were evaluated before and after the training program using an isokinetic dynamometer.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

the absence of heart disease, arterial hypertension, diabetes mellitus or any musculoskeletal condition of the lower extremities that precluded participation in the recommended training protocols and testing, no use of any dietary supplements during the study and for at least 2 months prior to the study and running more than 20 kilometers per week.

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Exclusion criteria

Age <20 or >40, history of cardiac disease, history of heart failure, history of coronary artery disease, history of peripheral artery disease, presence/history of varicose veins, history of hypertension, history of diabetes mellitus, history of pulmonary disease, history of pulmonary embolism, history of hematological disease, history of previous deep vein thrombosis, pregnancy, use of oral contraceptives, use of anticoagulants, history of previous surgery in the lower extremity, body mass index >25, history of cancer, presence of lymphedema, history of lymphadenectomy, history of trauma in the lower extremity within the last 6 months or 1 year.

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Treatment and study plan

the isokinetic training group with blood flow restriction

Device

The isokinetic training protocol for the knee flexor and extensor muscles consisted of 3 sets of 10 repetitions in 60°/sec and 3 sets of 30 repetitions in 180°/sec for 8 weeks, 2 times per week for 16 sessions.

the isokinetic training group without blood flow restriction

Device

The isokinetic training protocol for the knee flexor and extensor muscles consisted of 3 sets of 10 repetitions in 60°/sec and 3 sets of 30 repetitions in 180°/sec for 8 weeks, 2 times per week for 16 sessions.

Primary outcomes

  1. Evaluation of lower extremity muscle strength and muscular endurance using isokinetic dynamometry in runners who met the inclusion criteria for the study.

    Time frame: Baseline and 8 weeks

    Isokinetic knee flexor and extensor muscles strength and endurance were evaluated with the isokinetic dynamometer. All the athletes underwent twice a week for 8 weeks of isokinetic training protocol. Both groups performed the same isokinetic training protocol. Blood flow restriction was applied to the BFR group while the athletes doing isokinetic training protocol, but not to the control group. Isokinetic knee flexor and extensor muscles strength and endurance were re- evaluated at the end of the intervention (48 hours after the last training session).

Sponsors and collaborators

Lead sponsor

Bihter Aslanyurek

Other

Registry information

Official study title

The Effect of 8-week Isokinetic Training Combined with Blood Flow Restriction on Muscle Strength and Endurance in Runners

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Nov 7, 2024
Registry last updated
Nov 7, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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