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Completed

NCT Number: NCT07462520

Effects of Blood Flow Restriction vs. High-Load Resistance Training on Arm Strength

This study investigated the effects of low-load resistance training combined with blood flow restriction (BFRT) compared to traditional high-load resistance training on arm muscle strength and isokinetic contraction parameters in healthy young adults. Participants were prospectively assigned to either a low-load BFRT group or a high-load resistance training group for a 7-week intervention period. Muscle strength and isokinetic peak torque were assessed before and after the intervention. The primary objective was to determine whether low-load BFRT produces comparable improvements in muscle strength and isokinetic performance to high-load resistance training.

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Key information

Age range

18 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Gazi University

Ankara, Turkey (Türkiye)

About this study

his interventional study was designed to compare the effects of low-load blood flow restriction resistance training (LL-BFRT) and high-load resistance training (HL-RT) on arm muscle strength and isokinetic contraction parameters in healthy individuals.

A total of 22 healthy young adults were prospectively assigned to either a low-load BFRT group or a high-load resistance training group. The intervention lasted 7 weeks. The low-load BFRT group performed resistance exercises at 30% of one-repetition maximum (1RM) combined with individualized blood flow restriction pressure, while the high-load group trained at 70% of 1RM without blood flow restriction.

Primary outcome measures included isokinetic peak torque values of the elbow flexors and extensors. Secondary outcomes included muscle strength assessments. All participants completed pre-intervention and post-intervention evaluations.

The study aimed to determine whether low-load BFRT can induce strength and performance adaptations comparable to traditional high-load resistance training, offering an alternative training strategy when high mechanical loads are not desirable.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy individuals between the ages of 18 and 40
  • Individuals not taking any dietary supplements
  • Individuals not taking a substance containing anabolic ingredients
  • Individuals subjected to a resistance training program for at least 6 months
  • Individuals not performing aerobic training for more than 30 minutes per day
  • Individuals training with a personal trainer

Exclusion criteria

  • Individuals with a skeletal muscle injury in the last 6 months
  • Individuals who have undergone a surgical operation
  • Individuals with chronic high blood pressure and cardiovascular disease
  • Individuals who miss three consecutive training sessions
  • Individuals with chronic cardiovascular disease

Treatment and study plan

Low Load Blood Flow Restriction Training

Procedure

Low-load resistance training performed at 30% of one-repetition maximum with individualized blood flow restriction pressure.

High Load Resistance Training

Procedure

Traditional resistance training performed at 70% of one-repetition maximum without blood flow restriction.

Primary outcomes

  1. Arm Muscle Strength

    Time frame: Baseline and after 7 weeks of training

    Isokinetic peak torque of elbow flexor and extensor muscles measured using an isokinetic dynamometer.

Secondary outcomes

  1. Isokinetic Contraction Parameters

    Time frame: Baseline and after 7 weeks of training

    Isokinetic peak torque (Nm) of elbow flexor and extensor muscles measured using an isokinetic dynamometer.

Sponsors and collaborators

Lead sponsor

Gazi University

Other

Registry information

Official study title

The Effect of Blood Flow Restriction Resistance Exercise on Arm Muscle Strength and Isokinetic Contraction Parameters

Acronym: BFRT-ARM

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Mar 10, 2026
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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