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NCT Number: NCT06844058

Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression

This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression. The study will enroll 90 participants with mild to moderate anxiety and depression, who will be randomly assigned to one of three groups: (1) IEH intervention, (2) SEH intervention, or (3) control group (no intervention). Participants in the intervention groups will receive 12 weekly hypnotherapy sessions, each lasting 60 minutes. The primary outcomes include changes in Beck Depression Inventory-II (BDI-II) and Beck Anxiety Inventory (BAI) scores from baseline to post-intervention and at a 4-week follow-up.

The study will also assess whether religious belief levels moderate the effects of the intervention using the OK-Religious Attitude Scale. Data collection will be performed at Istanbul Nişantaşı University, and ethical approval has been obtained.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

This randomized controlled trial evaluates the differential effects of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in alleviating symptoms of anxiety and depression among religious Muslim adults. The primary objective is to examine whether the integration of Islamic religious elements into Ericksonian hypnotherapy enhances clinical outcomes compared to its standard application.

The study follows a parallel-group design with three arms: IEH, SEH, and a no-intervention control. Ninety participants (30 per group) are randomized using stratified block randomization based on age and gender. All intervention sessions are manualized, delivered by trained clinical psychologists, and conducted weekly over 12 weeks (each lasting 60 minutes).

IEH sessions incorporate culturally and religiously adapted therapeutic elements, such as Quranic metaphors, Islamic imagery, and spiritual affirmations, in line with the Ericksonian framework. SEH sessions utilize traditional hypnotic techniques including metaphorical storytelling, guided imagery, and indirect suggestions, without religious content.

Primary outcome measures include changes in Beck Depression Inventory-II (BDI-II) and Beck Anxiety Inventory (BAI) scores from baseline to Week 12 (post-intervention) and Week 16 (follow-up). Secondary analyses will investigate whether religiosity levels (measured via the OK-Religious Attitude Scale) moderate treatment effects. Blinded outcome assessors will ensure unbiased data collection.

This study addresses the need for culturally responsive mental health interventions within Muslim populations. Ethical approval was obtained from the İstanbul Nişantaşı University Ethics Committee (Approval No: 20250103-27). Results are expected to contribute to evidence-based development of spiritually integrated psychotherapeutic models for anxiety and depression.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Muslim individuals aged 18-65 years.
  • Mild to moderate anxiety and/or depression symptoms (assessed via Beck
  • Depression Inventory-II (BDI-II) and Beck Anxiety Inventory (BAI)).
  • No formal psychiatric diagnosis but experiencing psychological distress.
  • High religious belief levels, assessed via OK-Religious Attitude Scale.
  • Not currently receiving psychotherapy or psychotropic medication.
  • Ability to give informed consent and complete the study requirements.

Exclusion criteria

  • Severe psychiatric disorders (schizophrenia, bipolar disorder, severe MDD).
  • Current use of psychotropic medication or undergoing psychotherapy.
  • History of substance abuse or dependence.
  • Diagnosed dissociative disorders (contraindications for hypnosis).
  • Cognitive impairment affecting comprehension of intervention.
  • Severe medical conditions that may interfere with participation.

Treatment and study plan

Islamic-Oriented Ericksonian Hypnotherapy (IEH)

Behavioral

This intervention involves 12 weekly sessions (60 minutes each) of Ericksonian hypnotherapy integrated with Islamic religious elements. Sessions incorporate:

Quranic metaphors and Islamic imagery Spiritual affirmations to enhance relaxation and emotional regulation Faith-based guided hypnosis adapted to cultural and religious beliefs Techniques such as indirect suggestions, therapeutic storytelling, and guided imagery The intervention is designed for Muslim participants with mild to moderate anxiety and depression.

Standard Ericksonian Hypnotherapy (SEH)

Behavioral

Participants receive 12 weekly sessions (60 minutes each) of standard Ericksonian hypnotherapy, which includes:

Metaphorical storytelling and guided imagery Indirect hypnotic suggestions to promote psychological flexibility Relaxation techniques to reduce anxiety and depressive symptoms Unlike the Islamic-Oriented Hypnotherapy (IEH), this intervention does not integrate religious or faith-based elements.

Primary outcomes

  1. Beck Depression Inventory-II (BDI-II)

    Time frame: Baseline, Week 12 (post-intervention), Week 16 (follow-up)

    The study evaluates the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) vs. Standard Ericksonian Hypnotherapy (SEH) vs. No Intervention in reducing depressive symptoms. Depression severity will be assessed using the Beck Depression Inventory-II (BDI-II), comparing baseline, post-intervention (Week 12), and follow-up (Week 16) scores.

  2. Beck Anxiety Inventory (BAI)

    Time frame: Baseline, Week 12, Week 16

    The study measures reductions in anxiety symptoms among participants receiving IEH, SEH, or no intervention. Anxiety severity will be assessed using the Beck Anxiety Inventory (BAI), comparing scores from baseline to post-intervention and follow-up.

Study contacts

Contact information is provided by the study sponsor or research team.

Gözde Mert, Phd

CONTACT

[email protected]

+905359403399

Metin Çınaroğlu, Phd

CONTACT

[email protected]

+905324732070

Sponsors and collaborators

Lead sponsor

Istanbul Nisantasi University

Other

Registry information

Official study title

Efficacy of Islamic-Oriented Ericksonian Hypnotherapy vs. Standard Ericksonian Hypnotherapy in Reducing Anxiety and Depression: A Randomized Controlled Trial

Acronym: IEH-RTC

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 25, 2025
Registry last updated
Mar 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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