Is The Pain in Lipedema Patients Neuropathic Pain?

This study is a descriptive cross-sectional study. 42 patients will be included to study who apply to the outpatient clinic of Dokuz Eylul University Faculty of Medicine, Department of Physical Therapy and Rehabilitation, and who are diagnosed or followed up with the diagnosis of lipoedema, aged between 18- 65 years. For the control group, 42 patients who had shoulder pain for less than 3 months and is diagnosed with acute subacromial impingement will be included as the nociceptive pain model. The LANSS Pain Scale and Pain Detect Questionnaire to assess patients' pain characteristics, the Nottingham Health Profile to assess quality of life, and the Hospital Anxiety and Depression Scale to detect the presence of depression and anxiety will be completed by patients. LANSS Pain Scale is an evaluation form that helps to understand whether the nerves carrying pain signals are working normally, and it consists of two parts, including a pain questionnaire and a sensory evaluation. As a result of the calculation made according to answers, a score above 12 is associated with the presence of neuropathic pain. Pain Detect Questionnaire consists of questions about characteristics, severity and spread of the pain, and it provides the opportunity to score with 5 options as none, very mild, mild, moderate, severe, very severe. This survey, which consists of 38 points in total; in the presence of above 19 points, the neuropathic pain component is interpreted as possible. Nottingham Health Profile consists of 6 sections and a total of 38 questions evaluating patients' pain, emotional reaction, sleep, social isolation, physical activity and energy. In this questionnaire, where the highest score is 600 points, a high score is associated with a deterioration in quality of life. Hospital Anxiety and Depression Scale consists of 14 questions about anxiety and depression and 4 options for each question. According to the results, 0-7 points were interpreted as normal, 8-10 points were considered borderline, and 11 points and above were interpreted as abnormal. According to results of questionnaires, the datas will be compared with statistical analysis. As a result, the investigators aim to say that lipedema pain is or is not a neurpathic pain.

Inclusion criteria

• Ages between 18-65
• Diagnosed with lipoedema
• Those who agreed to participate in the study
• To be at the appropriate sociocultural level to participate in the study
• For the control group, the patient has a diagnosis of acute subacromial impingement syndrome

Exclusion criteria

• Having type 1 or type 2 diabetes
• Patients with uncontrolled thyroid dysfunction
• Patients with chronic venous insufficiency and/or lymphedema
• Patients with acute or chronic renal failure
• Heart failure
• Having cancer or continuing cancer treatment
• Diagnosed with polyneuropathy
• Those with radiculopathy
• Patients with advanced degenerative joint disease in the affected extremity
• Those who have received antiepileptic, antidepressant medication in the last 6 months
• Persons with visual and hearing impairments that impair adaptation to work
• Patients who are illiterate and have cognitive impairment that will prevent them from giving written consent will not be included in the study.