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Completed

NCT Number: NCT07046598

Is The Level of Muscle Damage After The Drop Jump Protocol Affected By Body Weight and BMI?

This study investigated whether muscle damage induced by a drop jump protocol varies based on participants' body weight and BMI. Fifty healthy adults were divided into normal-weight and overweight groups. All participants completed a standardized drop jump protocol, and blood samples were collected before, immediately after, and 24 hours after exercise. Creatine kinase (CK) and lactate dehydrogenase (LDH) levels were analyzed as biomarkers of muscle damage.

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Key information

Conditions

Body Mass Index Creatine Kinase Lactate Dehydrogenases Muscle Damage Physical Exertion

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Sakarya University of Applied Sciences, Faculty of Sport Sciences, Exercise and Sports Sciences Education, Application and Research Centre

Serdivan, Sakarya, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults aged 18-30
  • Normal or overweight BMI (18-35 kg/m²)
  • At least 2 days/week of physical activity
  • No regular jump training

Exclusion criteria

  • Use of medications or supplements
  • History of musculoskeletal injury
  • Smoking or alcohol consumption during study period

Treatment and study plan

Drop Jump Protocol

Behavioral

A standardized drop jump (DJ) protocol involving 100 total jumps from a 60 cm platform. Participants performed five sets of 20 jumps, with a 10-second rest between jumps and a 2-minute rest between sets. The protocol was designed to induce muscle damage through eccentric loading.

Primary outcomes

  1. Change in Creatine Kinase (CK) Levels

    Time frame: Baseline (pre-exercise), immediately post-exercise, and 24 hours post-exercise

    Serum creatine kinase (CK) concentrations measured at three time points: before the exercise protocol, immediately after the protocol, and 24 hours post-exercise. CK is a biomarker of muscle damage. Blood samples were analyzed using a standard biochemical analyzer.

  2. Change in Lactate Dehydrogenase (LDH) Levels

    Time frame: Baseline (pre-exercise), immediately post-exercise, and 24 hours post-exercise

    Serum lactate dehydrogenase (LDH) concentrations measured at three time points: before the exercise protocol, immediately after the protocol, and 24 hours post-exercise. LDH is used to evaluate exercise-induced muscle damage. Blood samples were centrifuged and analyzed using standardized laboratory techniques.

Sponsors and collaborators

Lead sponsor

Melike Nur Eroğlu

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jul 1, 2025
Registry last updated
Jul 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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