Is Pulse Co-Oximetry a Reliable Alternative to Invasive Hemoglobin Measurement in Pediatric Neurosurgical Procedures?

The study evaluated the diagnostic accuracy and clinical utility of continuous SpHb across a comprehensive pediatric age spectrum-ranging from neonates to adolescents-undergoing high-risk neurosurgical procedures (cranial and spinal) characterized by significant potential for blood loss.

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Key information

Conditions

Anemia (Diagnosis) Anemia Disease Hematologic Diseases Hemic and Lymphatic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

2 month–16 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Selcuk University

Konya, Selçuklu, 42130, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ASA I-IV,
Scheduled for elective complex spinal surgery or cranial procedures under general anesthesia

Exclusion criteria

congenital heart disease
requirement for emergency surgery
pre-existing peripheral circulatory disorders

Treatment and study plan

Masimo Radical-7® Pulse CO-Oximeter

Device

Continuous non-invasive measurement of total hemoglobin (SpHb) using a pulse co-oximetry sensor during the surgery.

Primary outcomes

Agreement and Correlation between Non-invasive Hemoglobin (SpHb) and Invasive Arterial Hemoglobin (Hb) levels.

Time frame: Intraoperative period (from induction of anesthesia to extubation, approximately 2-5 hours

Sponsors and collaborators

Lead sponsor

Selcuk University

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Jan 20, 2026
Registry last updated: Jan 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed