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NCT Number: NCT06235359

Is Intercostal Tube Enough in Management of Empyema

Is intercostal tube enough in management of empyema ?

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Empyema refers to presence of pus in the pleural space -Causes Primary: bacterial Pneumonia (staph aureus, strept pneumonia , H.influenza) , TB

Secondry :

PostTraumati postoperative :open heart , esophageal, mediastinum , lung rupture of lung absess

-pathophysiology and stages During an inflammatory process such as pneumonia, there is an increase in fluid production in the pleural cavity known as the exudate stage. As the disease progresses microorganisms, usually bacteria, can colonize the fluid and generated an empyema. This fluid is characterized by elevated lactate dehydrogenase, proteins, neutrophils, and dead cells. Macroscopically is a thick opaque fluid found in the fibrinopurulent stage. After the resolution of the infection and as a consequence of the inflammation, there is a process of fibrosis that can lead to restriction of the lung parenchyma which is stage of chronic organization

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients admitted to Assuit university Hospital and diagnosed with empyema

Exclusion criteria

  • Patient diagnosed with Post-operative empyema
  • Patient diagnosed with post traumatic empyema
  • Patient diagnosed with Bronchopleural fistula
  • Patient diagnosed with TB

Treatment and study plan

intercostal tube

Device

A chest tube is a hollow, flexible tube placed into the chest. It acts as a drain.

Chest tubes drain blood, fluid, or air from around your lungs, heart, or esophagus.

The tube around your lung is placed between your ribs and into the space between the inner lining and the outer lining of your chest cavity. This is called the pleural space. It allows your lungs to fully expand.

Primary outcomes

  1. To find best way to drain the pus in the pleural space

    Time frame: baseline

    To find best way to drain the pus in the pleural space

Study contacts

Contact information is provided by the study sponsor or research team.

Islam abdelfatah, resident

CONTACT

[email protected]

01024984239

Mahmoud khairy, professor

CONTACT

[email protected]

01098935293

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jan 31, 2024
Registry last updated
Jan 31, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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