Skip to main content
OpenTrials
Completed

NCT Number: NCT05572125

Iron Therapy in Erythropoietic Protoporphyria

Giving oral iron to patients with erythropoietic protoporphyria (EPP) who is iron deficient is thought to be beneficial. This is, however, not well documented. The purpose of this study is to investigate the effect and safety of oral iron in patients with EPP who is taking iron tablets due to iron deficiency.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Erythropoietic Protoporphyria Anemia Anemia, Hypochromic Anemia, Iron-Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities Digestive System Diseases Genetic Diseases, Inborn Hematologic Diseases Hemic and Lymphatic Diseases Iron Deficiencies Iron Metabolism Disorders Iron-deficiency Liver Diseases Metabolic Diseases Nutritional and Metabolic Diseases Porphyrias Porphyrias, Hepatic Protoporphyria, Erythropoietic Skin Diseases Skin Diseases, Genetic Skin and Connective Tissue Diseases

Age range

15 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bispebjerg Hospital

Copenhagen, 2400, Denmark

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with EPP
  • Taking standard dose of iron tablets due to iron deficiency

Exclusion criteria

  • Pregnant
  • Lactating

Treatment and study plan

Primary outcomes

  1. Change in erythrocyte protoporphyrin concentration

    Time frame: Before treatment and after 6-8 weeks of treatment

Secondary outcomes

  1. Change in hemoglobin and iron parameters

    Time frame: Before treatment and after 6-8 weeks of treatment

  2. Adverse event

    Time frame: 6-8 weeks of treatment

Sponsors and collaborators

Lead sponsor

Bispebjerg Hospital

Other

Collaborators

  • Alfred Benzon Foundation

Registry information

Official study title

Oral Iron Therapy in Erythropoietic Protoporphyria

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Oct 7, 2022
Registry last updated
Feb 23, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.