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NCT Number: NCT07073989

Investigating the Impact of Afferent Stimulation on Proprioceptive Function in Post-Stroke Rehabilitation

The objective of this study is to assess the functionality of a sensory stimulation device that uses mechanical vibrations and low-intensity electrical currents to deliver proprioceptive feedback to stroke patients regarding their movements.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidad Rey Juan Carlos

Móstoles, Madrid, 28933, Spain

Location status: Recruiting

Location contact

Julio S Lora Millan, PhD in Automation and Robotics

CONTACT

[email protected]

914884584 ext. 4584

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • For healthy subjects:
  • No neurological or orthopedic conditions affecting upper limb movement.
  • No surgical interventions on the upper limbs within the past 6 months.
  • General physical condition adequate to perform the session.
  • Cognitive abilities sufficient to understand and carry out the experimental procedure.
  • For stroke survivors:
  • Ischemic or hemorrhagic stroke resulting in motor impairments in the upper limb.
  • Chronic stroke condition.
  • Subjects with sufficient cognitive abilities to follow instructions and actively participate in the therapy.
  • Mini-Mental State Examination (MMSE) score > 24.
  • Subjects presenting hemiparesis and mild-to-moderate impairment in the upper limb (score on the Fugl-Meyer Motor Assessment for the upper limb, sections A-D, between 35 and 53 points). The maximum score on the FM scale is 66, with the following severity classifications:
  • 0-15: severe impairment
  • 16-34: moderate-to-severe impairment
  • 35-53: mild-to-moderate impairment
  • 54-66: mild impairment 6. Subjects presenting upper limb hypertonia with a score below 3 on the Modified Ashworth Scale.
  • Subjects who have signed the informed consent document to voluntarily participate in the experiments.

Exclusion criteria

  • Acute musculoskeletal disorders.
  • Peripheral vascular diseases.
  • Acute cardiopulmonary conditions.
  • Acute neurological disorders.
  • Restricted mobility of upper limb joints due to any cause.
  • Pain as a cause of impaired upper limb mobility.

Treatment and study plan

Afferent stimulation

Device

Stimulation applied through mechanical vibration or low-intensity electric currents

Primary outcomes

  1. Motor illusion

    Time frame: Periprocedural

    Motor illusion is evaluated by instructing the patient to replicate the movement they experienced in the contralateral limb. Inertial sensors will be placed in such limb to acquire the movement performed by the subject.

Study contacts

Contact information is provided by the study sponsor or research team.

Julio S. Lora Millán, PhD in Automation and Robotics

CONTACT

[email protected]

914880000 ext. 4584

Sponsors and collaborators

Lead sponsor

Julio S. Lora Millán

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 20, 2025
Registry last updated
Jul 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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