Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06880861

Investigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult Cancers

This study evaluates relationships among physical activity, thinking, and memory after cancer treatment in survivors of adolescent and young adult cancers.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Hematopoietic and Lymphatic System Neoplasm Behavior Malignant Solid Neoplasm Motor Activity Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (aged 18+ years)
  • Primary diagnosis of cancer when 15-39 years-old
  • Access to a desktop computer or laptop with reliable internet access
  • No gross motor impairments that prohibit ambulation
  • Willing to complete study requirements
  • English speaking

Exclusion criteria

  • Diagnosed with nonmelanoma skin cancer only
  • Not diagnosed with cancer in adolescent and young adult (AYA) age range of 15-39 years
  • Scheduled travel during the study period that is not indicative of individual's normal schedule

Treatment and study plan

Non-Interventional Study

Other

Non-Interventional Study

Primary outcomes

  1. Cognitive performance on Stroop task

    Time frame: Up to 4 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions.

Secondary outcomes

  1. Cognitive performance on Visual Memory Test

    Time frame: 2 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions.

  2. Cognitive performance on Verbal Memory Test

    Time frame: 2 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions.

  3. Cognitive performance on Symbol Digit Coding Test

    Time frame: 2 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions.

  4. Cognitive performance on Shifting Attention Test

    Time frame: 2 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions.

  5. Cognitive performance on Continuous Performance Test

    Time frame: Up to 4 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games").

  6. Cognitive performance on Reasoning Test

    Time frame: 2 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions.

  7. Cognitive performance on Four Part Continuous Performance Test

    Time frame: 2 weeks

    Assessed using the CNS Vital Signs computerized testing platform ("brain games"). CNS Vital Signs is a computerized neuropsychological/neurocognitive assessment platform used by clinicians and researchers to objectively evaluate brain function and neurocognitive status, offering a range of tests and tools for assessment and management of various neurological and behavioral conditions.

  8. Self-reported cognition - FACT-COG

    Time frame: 2 weeks

    Evaluated using the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-COG), a 37-item questionnaire assessing cognitive impairment, cognitive abilities, and quality of life over the past 7 days. Responses are on a 5-point scale (Never; About once a week; Two to three times a week; Nearly every day; Several times a day). Higher scores generally indicate better self-reported cognition.

  9. Average weekly minutes of physical activity

    Time frame: 2 weeks

    Moderate-to-vigorous physical activity (MVPA) will be measured using an accelerometer (activPAL) which participants will wear on their non-dominant thigh for 7 consecutive days.

Study contacts

Contact information is provided by the study sponsor or research team.

Clinical Trials Referral Office

CONTACT

[email protected]

855-776-0015

Melissa Cole

CONTACT

mailto:[email protected]

480-574-4052

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Acronym: IMPACT

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 18, 2025
Registry last updated
May 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.