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OpenTrials
Completed

NCT Number: NCT05060926

Intubation Prediction in COVID-19 Patients Treated With Awake Prone Positioning

Retrospective study in Sars-Cov 2 patients hospitalised in ICU. We aim to explore the effects of Awake prone positioning on oxygenation and intubation rate.

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Key information

Conditions

Acute Hypoxemic Respiratory Failure Respiration Disorders Respiratory Insufficiency Respiratory Tract Diseases SARS-CoV-2 Virus

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Lausanne University Hospitals

Lausanne, Canton of Vaud, 1011, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Sars-CoV-2 pneumonia
  • ICU stay
  • Severe hypoxemia but non intubated

Exclusion criteria

  • Intubated before admission
  • Denied consent for data analysis
  • Do not intubate order at ICU admission

Treatment and study plan

Awake Prone Positioning

Procedure

Awake prone position as long as possible according to the patients' tolerance

Primary outcomes

  1. Intubation rate

    Time frame: Once between ICU admission and extubation

Secondary outcomes

  1. Alveolo-arterial gradient change

    Time frame: Within 6 hours before and 6 hours after each pronation

  2. Blood gas analysis

    Time frame: Within 6 hours before and 6 hours after each pronation

  3. Respiratory pattern

    Time frame: Within 6 hours before and 6 hours after each pronation

  4. Mortality

    Time frame: Up to 28 days from ICU admission

Sponsors and collaborators

Lead sponsor

University of Lausanne Hospitals

Other

Registry information

Official study title

Intubation Prediction in Sars-CoV-2 Patients Treated With Awake Prone Positioning

Acronym: Intub_prone

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Sep 29, 2021
Registry last updated
Jun 3, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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