Centre for Chronobiology, Psychiatric Hopspital of the University of Basel
Basel, 4002, Switzerland
NCT Number: NCT05485415
The main objective of the study is to improve subjective sleep quality using a multimodal intervention with an intervention and a control group. The multimodal intervention aims to improve circadian Zeitgeber strength. This will be achieved by optimizing daily light exposure, sleep, physical activity, and mealtimes.
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Notify Me65 year and older
All sexes
Interventional
Not applicable
Basel, 4002, Switzerland
The study lasts for 14 months and contains 6 visits. After the screening visit at the Centre for Chronobiology, Basel, Switzerland, participants are assigned to either the intervention or the control group which is followed by a 7-day baseline week at home and a co-design meeting to provide instructions to the intervention and the control group. At the occasion of 2 visits (spread over 6 months) at the participants' homes, different measurements will be performed such as saliva collection, questionnaires, cognitive performance tests, light and rest-activity measures. After the last visit at home, participants come for the second blood sample at the study centre. A follow-up visit 6 months after completion of the last data collection will provide qualitative feedback by the participants.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
at least 65 years old women and men
Exclusion criteria
Participants in the intervention group will receive personalised advice on sleep, light exposure, meal times and physical activity.
General sleep advice
Time frame: 6 months
Pittsburgh Sleep Quality Index (Score > 5 indicates poor sleep)
Time frame: 6 months
Derived from Activity Watches
Time frame: 6 months
Visual Analogue Scales
Time frame: 6 months
Circadian phase marker
Time frame: 6 months
Pupil response to chromatic light stimuli
Time frame: 6 months
HbA1c concentration (blood)
Time frame: 6 months
Age marker
Time frame: 6 months
Cognitive Function
Mirjam Münch
Network
Personalised Circadian Intervention Study in Elderly With Sleep Problems
Acronym: CIEL
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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