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NCT Number: NCT07311096

Interscalene Block Versus Serratus Posterior Superior Intercostal Plane Block for Arthroscopic Shoulder Surgery

This randomized controlled trial aims to compare the effectiveness of interscalene (ISB) and serratus posterior superior intercostal plane block (SPSIP) for postoperative analgesia in patients undergoing elective arthroscopic shoulder surgery. The primary outcome is total 24-hour opioid consumption. Secondary outcomes include pain scores, hemidiaphragmatic paresis incidence and severity, duration of analgesia, and changes in lung function. Participants are randomized into ISB or SPSIP groups; blocks are performed under ultrasound guidance. Postoperative pain is managed with patient controlled analgesia(PCA).

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Key information

Conditions

Shoulder Pain Agnosia Arthralgia Joint Diseases Musculoskeletal Diseases Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Perceptual Disorders Postoperative Complications Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Erzurum Regional Training Research Hospital

Erzurum, Yakutiye, 25100, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Agreeing to participate in the study
  • The American Society of Anesthesiologists I-III
  • Scheduled for elective unilateral arthroscopic shoulder surgery

Exclusion criteria

  • Refusal to participate in the study
  • Allergy to the medications to be used
  • History of serious heart, kidney or liver disease
  • Neurological deficits or neuropathy
  • History of anticoagulant use
  • Pre-existing operative respiratory dysfunction
  • Having chronic shoulder pain
  • Being about to undergo open surgery

Treatment and study plan

Interscalene Brachial Plexus Block (ISB)

Procedure

Patients receive ultrasound-guided ISB before arthroscopic shoulder surgery. 15 ml of 0.25% bupivacaine is injected using a 22 Gauge 50 mm needle with posterior in-plane approach, targeting C5-C6 roots.

Serratus Posterior Superior Intercostal Plane Block (SPSIP)

Procedure

Patients receive ultrasound-guided SPSIP interfascial block in sitting position before surgery. Using a 22 Gauge 10 mm needle, 30 ml of 0.25% bupivacaine is injected between serratus posterior muscle and second rib.

Primary outcomes

  1. Total 24-Hour Postoperative Opioid Consumption

    Time frame: 0-24 hours postoperatively

    Total intravenous opioid consumption recorded for each patient during the first 24 hours after arthroscopic shoulder surgery, including any rescue analgesia administered.

Secondary outcomes

  1. Incidence and Severity of Hemidiaphragmatic Paresis

    Time frame: Pre-block and 30 minutes post-block

    Ipsilateral hemidiaphragmatic function evaluated by M-mode ultrasonography before block and 30 minutes after block completion. Paresis classified as none (<25% reduction), partial (25-75% reduction), or complete (>75% reduction or paradoxical movement).

  2. Duration of Analgesia

    Time frame: Time interval from block completion to initiation of IV PCA fentanyl in each patient

    0-24 hours post-block

  3. Pulmonary Function Changes (FEV1)

    Time frame: Pre-block and 30 minutes post-block

    Pulmonary function measured with bedside spirometry pre-block and 30 minutes post-block. Forced expiratory volume in 1 second (FEV1) recorded; each measurement performed three times and mean value used.

  4. Pulmonary Function Changes (FVC)

    Time frame: Pre-block and 30 minutes post-block

    Pulmonary function measured with bedside spirometry pre-block and 30 minutes post-block. Forced vital capacity (FVC) recorded; each measurement performed three times and mean value used.

Sponsors and collaborators

Lead sponsor

Erzurum Regional Training & Research Hospital

Other Gov

Registry information

Official study title

Comparison of the Effectiveness of Interscalene Nerve Block and Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Arthroscopic Shoulder Surgery

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Dec 30, 2025
Registry last updated
Dec 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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