Intermittent Fasting in Hypertriglyceridemic Overweight or Obese Subjects

a randomized clinical trial will be conducted in National Nutrition and Food Technology Research Institute, Tehran, Iran. after the review of inclusion and exclusion criteria, a written consent form will be completed. the participants will be 90 hypertriglyceridemic patients aged between 18-60. half of the participants will be under intermittent low-calorie diet which they will have 3 alternate days in the week eating only 30% of their total energy requirement and on the other days of the week they receive a total calorie of 100% of their energy requirement , therefore there will be a total of -210% TEE reduction in their received energy in the week. the other group will be under continuous calorie restriction meaning on all the days of the week they will be eating 70% of their total energy requirement resulting in a total of -210% TEE reduction in their received energy in the week. both groups will receive 3 consultation sessions with a nutritionist, also to prevent any deficiency, multi-vitamin-mineral supplements will be given to both groups participants.

Inclusion criteria

• hypertriglyceridemic : TG>150 mg/dL
• BMI>24.9
• age 18-60
• non-smoker
• haven't been under any diet at least 3 months before participating in the study
• not starting any new exercise program or changing the previous exercise while in the study

Exclusion criteria

• chronic kidney disease stage 3-5
• consuming Insulin or Insulin-inducing drugs.
• consuming triglycerides lowering drugs or Omega 3
• a history of cholecystitis
• Heart arrhythmia