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OpenTrials
Completed

NCT Number: NCT07705516

Interfascial Abdominal Wall Block for Gynecological Laparoskopy: A Randomized Clinical Trial

The purpose of this study is to evaluate the clinical efficacy of combining ultrasound-guided bilateral rectus sheath blocks (RSB) and quadratus lumborum blocks (QLB) compared to using a quadratus lumborum block alone for postoperative analgesia in patients undergoing laparoscopic gynecological surgeries.

The primary objective is to assess movement-evoked pain scores in the early postoperative period. Secondary objectives include the evaluation of postoperative opioid consumption, intraoperative hemodynamic stability, and the overall incidence of side effects. Investigators hypothesize that the combined interfacial abdominal wall block technique will provide superior pain relief and reduce opioid requirements during recovery.

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Key information

Conditions

Postoperative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Pelvic Pain Postoperative Complications Signs and Symptoms

Age range

25 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Medical and Diagnostic Center "MEDION" LLC

Poltava, Poltava Oblast, 36039, Ukraine

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Scheduled for elective gynecological video-laparoscopic surgery.
  • ASA physical status І-ІІ.
  • Age between 18 and 65 years.
  • Patient's informed consent to participate in the study

Exclusion criteria

  • Known allergy or contraindications to local anesthetics.
  • Infection at the potential needle insertion sites.
  • Coagulopathy or ongoing anticoagulant therapy.
  • Conversion to open laparotomy during surgery.
  • Severe cognitive impairment or psychiatric disorders.

Treatment and study plan

Bilateral QLB and RSB

Procedure

Preoperative regional anesthesia. Bilateral QL block combined with bilateral RS block. Ultrasound-guided technique. Using local anesthetics.

Bilateral QLB alone

Procedure

Preoperative regional anesthesia. Isolated bilateral QL block. No rectus sheath block. Ultrasound-guided technique. Using local anesthetics.

Primary outcomes

  1. Postoperative pain intensity

    Time frame: At 2, 4, 6, 12, and 24 hours postoperative assessment

    Visual Analog Scale (VAS) score. Scale from 0 to 10. 0 means no pain. 10 means worst pain. Lower scores sindicate less pain.

Secondary outcomes

  1. Total opioid consumption. Postoperative period. Measured in milligrams.

    Time frame: Within 24 hours after surgery.

    Total dose of opioid analgesics. Administered within 24 hours. Measured in milligrams (mg). Lower doses indicate better opioid-sparing effect.

Sponsors and collaborators

Lead sponsor

Medical and Diagnostic Center "MEDION" LLC

Other

Registry information

Official study title

Combined Rectus Sheath and Quadratus Lumborum Blocks Versus Quadratus Lumborum Block Alone for Movement-evoked Pain After Laparoscopic Gynecologic Surgery: a Prospective Randomized Open-label Trial

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 15, 2026
Registry last updated
Jul 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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