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OpenTrials
Completed

NCT Number: NCT00512395

Influence of Epidural Analgesia in Elective Laparoscopic Colorectal Resections

Epidural anaesthesia in open surgery is a effective method for analgesia and has a positive effect on postoperative resolution of ileus. In laparoscopic surgery, the role of epidural surgery is not established. This prospective observational trial evaluates the effect of epidural analgesia in patients undergoing elective, laparoscopic colorectal surgery.

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Key information

Conditions

Pain Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Triemli Hospital

Zurich, Switzerland

About this study

All patients with elective, laparoscopic colorectal resection between November 2004 and January 2007 were included in the trial. The decision for epidural analgesia was made by the anaesthetist and the patient. Contraindications were previous back surgery, coagulopathy, severe spondylarthrosis and refusal by the patient as contraindications.

Primary outcome was subjective feeling postoperatively, assessed with a VAS for pain and cramps and amount of analgesics used. Secondary outcomes were duration of postoperative bowel dismotility (first flatus, first defecation, first solid food intake) and general and specific morbidity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • elective laparoscopic colorectal resection

Exclusion criteria

  • emergency surgery
  • preoperatively planned stoma formation

Treatment and study plan

epidural analgesia (Duracain/Fentanyl/Naropin)

Drug

naropin 0.3% or duracain 0.125% + Fentanyl via epidural catheter 4-12 ml/h

Primary outcomes

  1. pain (VAS), cramps (VAS) and quantity of analgesics

    Time frame: 8 days

Secondary outcomes

  1. duration of postoperative ileus morbidity

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Collaborators

  • Triemli Hospital

Registry information

Important dates

Study start
2004
Study completion
2007
First posted
Aug 7, 2007
Registry last updated
Mar 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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