Influence of Chronic Vascular Diseases on Transcranial Doppler Profiles in Critically Ill Patients

Inclusion criteria

for entry in the study:

• Sedated patient under mechanical respiratory assistance

Inclusion criteria

for entry in group 1: the patient meets at least one of the following criteria:

• The patient is a man over the age of 50 or a woman over the age of 60
• Hypercholesterolemia (LDL > 1.6 g/L, HDL < 0.4 g/L)
• Arterial hypertension for over 10 years (treated or systolic arterial pressure > 140 mmHG)
• Type 2 diabetes for over 10 years
• Active or former smoker in the past 3 years
• History of cardiovascular event (peripheral artery disease, heart attack, stroke/transient ischemic attack over 3 months ago)
• Chronic renal insufficiency with MDRD < 30 ml/min/1.73m^2

Inclusion criteria

for entry in group 2:

• The included patient is not in group 1

Exclusion criteria

• acute neurological disorder (brain trauma, infectious or immune meningitis, meningoencephalitis, ischemic or hemorrhagic stroke <3 months)
• pregnant woman
• person under guardianship
• prisoners
• recent carotid surgery (<1 month)