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Completed

NCT Number: NCT05763901

IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms

While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether conditions much more frequent in the pediatric population, the so-called "Paramorphisms or Dysmorphisms", may be associated with more or less noticeable changes in locomotor development.

On a few studies, flat feet and hyperlaxity has been correlated with a motor control delay or poorer motor performance, based on complex clinical tests or on stereophotogrammetry movement analysis.

Although promising, these preliminary studies, in addition to not providing information on the possible influence of other paramorphisms, such as varus and valgus of the knees, do not provide conclusive indications.

The aim of this study is to investigate, through clinical tests and wearable inertial units, the motor control of a pediatric population affected by Paramorphisms or Dysmorphisms and to compare them with a population of healthy controls, matched by age, taken from the recently developed control data set from Bisi and Stagni.

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Key information

Conditions

Genu Varum Angular Limb Deformity Animal Diseases Bone Diseases Cavus Foot Clubfoot Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Deficiency Diseases Flat Feet Flatfoot Foot Deformities Foot Deformities, Acquired Foot Deformities, Congenital Genu Valgum Genu Valgus Hyperkyphosis Hyperlordosis Joint Diseases Joint Instability Kyphosis Laxity of Ligament Limb Deformities, Congenital Lower Extremity Deformities, Congenital Malnutrition Musculoskeletal Abnormalities Musculoskeletal Diseases Nutrition Disorders Nutritional and Metabolic Diseases Scoliosis Idiopathic Sheep Diseases Spinal Curvatures Spinal Diseases Swayback Talipes Talipes Cavus Valgus, Talipes Varus; Talipes

Age range

6 year–17 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

IRCCS-Istituto Ortopedico Rizzoli

Bologna, 40136, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Born at term
  • Without known delay in motor development
  • Finding of one or more paramorphisms or dysmorphisms of the developmental age (flat or cavus foot, valgus or varus talipes, valgus or varus knee, scoliotic attitude or scoliosis, hyperkyphosis or hyperlordosis, generalized or focused hyperlaxity, heterometry of the AAII, torsional defects AAII)

Exclusion criteria

  • Preterm birth
  • Diagnosis of pathologies compromising motor control (Infantile Cerebral Palsy, Neuromuscular Diseases, Spina Bifida, Arthrogryposis, Genetic Syndromes)

Treatment and study plan

Clinical tests and motor control evaluation using Inertial Measurement Units

Diagnostic Test

Each patient is evaluated using clinical tests (Movement ABC2, Test of Motor Competence), a screening questionnaire (DCD-Q), and wearable Inertial Measurement Units to assess balance and motor control during a Natural Walking and Tandem Walking test.

Primary outcomes

  1. Evaluation and measurement of balance

    Time frame: Baseline

    Evaluation of balance using clinical tests ( Movement ABC2).

  2. Evaluation and measurement motor competence

    Time frame: Baseline

    Evaluation of motor competence using clinical tests (Test of Motor Competence, ).

  3. Measurement of balance

    Time frame: Baseline

    Measurement of balance assessing synchronicity from data obtained with Inertial Measurement Units.

  4. Measurement of motor competence

    Time frame: Baseline

    Measurement motor competence assessing automaticity from data obtained with Inertial Measurement Units.

Sponsors and collaborators

Lead sponsor

Istituto Ortopedico Rizzoli

Other

Registry information

Official study title

Evaluation of Motor Control During Developmental Age in Young Patients With Paramorphisms and Dysmorphisms Using Inertial Measurement Units

Acronym: MOTOR-CHILD

Important dates

Study start
2021
Primary completion
2024
Study completion
2024
First posted
Mar 10, 2023
Registry last updated
Dec 23, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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