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Completed

NCT Number: NCT01720472

Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository

The purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in order to develop a diverse cohort with specific physical and cognitive performance data paired with biological samples.

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Key information

Conditions

Aging Behavior Cognitive Functioning Fitness Motor Activity Physical Functioning

Age range

30 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bethesda Health Center, Charlotte, North Carolina, United States

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About this study

The MURDOCK Study, proposes this Horizon 2 study to collect a brief physical and cognitive performance assessment from 1,000 MURDOCK Registry participants. Blood sample aliquots will also be obtained. These physical and cognitive performance data, paired with -omics data from plasma and serum sample analyses, offer promise in the discovery of biomarkers for functional decline. This research will provide an important basis for our understanding of the physical, lifestyle, and genetic factors which, over the lifespan, contribute to changes in physical and cognitive capabilities as we age.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) or certain portions of Rowan, Mecklenburg, or Stanly counties in North Carolina for 6 or more months of the year.
  • Age 30 or older

Exclusion criteria

  • Female that is currently pregnant
  • Having had a heart attack, angina, congestive heart failure, or fluid in the lungs within the past 6 months
  • Participant that requires consent by a legally authorized representative
  • Participant that cannot walk 30ft without human assistance

Treatment and study plan

Biomarker studies

Genetic

Primary outcomes

  1. Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository

    Time frame: Upto 2 years or 24 months

    Factors associated with physical function and physical activity and change in physical activity and function over two-year follow-up.

Sponsors and collaborators

Lead sponsor

Duke University

Other

Registry information

Acronym: PPS

Important dates

Study start
2012
Primary completion
2018
Study completion
2018
First posted
Nov 2, 2012
Registry last updated
Apr 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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