Skip to main content
OpenTrials
Completed

NCT Number: NCT05323695

Implementation of a Depression Screening Intervention at a Transgender Health Clinic in Thailand

The study aims to develop and implement a depression screening intervention into routine HIV and sexual health service provision at a transgender health clinic in Thailand, and to explore the facilitators, barriers, feasibility and acceptability of the screening implementation.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Depressive Symptoms Behavior Behavioral Symptoms Depression

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Institute of HIV Research and Innovation

Pathum Wan, Bangkok, 10330, Thailand

About this study

The study will follow a mixed-methods approach that will incorporate quantitative and qualitative components. Aim 1 will involve the development and implementation of depression screening intervention at Tangerine Clinic. Aim 2 will involve semi-structured interviews with a purposive subset of participants who received the intervention and healthcare providers to explore the multilevel facilitators, barriers, feasibility and acceptability of the screening implementation. Aim 3 will evaluate the proportion of participants who are offered, accept, and receive the peer-led depression screening intervention, and the proportion who screen positive.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Thai nationality
  • Transgender women ≥18 years
  • Attending the Tangerine Clinic for routine care visits during the intervention period.
  • Can be a new or returning clients.

Exclusion criteria

  • Transgender women currently receiving care for a mental health diagnosis will be excluded from participating in this study.

Inclusion criteria

for healthcare providers:

  • Currently working at the Tangerine Clinic
  • Can be medical doctors, nurses, peer counselors and other members of the clinic management team involved in the routine delivery of HIV and health services to Transgender women.

Exclusion criteria

for healthcare providers

  • Not willing to participate in this study

Treatment and study plan

Depression Screening Intervention

Behavioral

All participants will be screened for depression using PHQ-2 and PHQ-9. Those screened positive for PHQ-2 but decline further screening with PHQ-9 will be assisted for further assessment or care. Those with mild to severe symptoms (score of 7 or higher on PHQ-9) will be assisted for further assessment or care with a psychiatrist.

Primary outcomes

  1. Intervention Acceptability: Number of participants who accepted intervention

    Time frame: Day 1

    Acceptability will be measured by the number of clients who were offered and accepted the intervention.

  2. Intervention Acceptability: Participants' perspective of the intervention through in-depth interviews

    Time frame: Day 1

    Acceptability will be assessed qualitatively through post-intervention in-depth interviews.

  3. Intervention Acceptability: Participants' perspective of the intervention through focus group discussion

    Time frame: Day 1

    Acceptability will be assessed qualitatively through post-intervention focus group discussion.

  4. Intervention Feasibility: Number of intervention completed

    Time frame: Day 1

    Feasibility will be measured by number of intervention completed. Point estimates of >50% of participants completed is considered as the minimum criteria for feasibility.

  5. Intervention Feasibility: Participants' perspective of the intervention through in-depth interviews

    Time frame: Day 1

    Feasibility will be assessed qualitatively through post-intervention in-depth interviews.

  6. Intervention Feasibility: Participants' perspective of the intervention through focus group discussion.

    Time frame: Day 1

    Feasibility will be assessed qualitatively through post-intervention focus group discussion.

  7. Number of participants screening positive for depression

    Time frame: Day 1

    Screening positive is defined as scoring 7 or greater on PHQ-9. The total possible score for PHQ-9 is 27, with 0-6 being minimum and indicating no depressive symptoms, 7-12 mild depression, 13-18 moderate depression, and 19-27 severe depression.

Sponsors and collaborators

Lead sponsor

Thai Red Cross AIDS Research Centre

Other

Collaborators

  • Fogarty International Center of the National Institute of Health
  • National Institutes of Health (NIH)
  • amfAR, The Foundation for AIDS Research

Registry information

Acronym: CHIMERA

Important dates

Study start
2021
Primary completion
2023
Study completion
2024
First posted
Apr 12, 2022
Registry last updated
Nov 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.