Impact of Pulse-enriched Foods on Cognitive Function and Cardiometabolic Health in Obese Adults

This is a multi-site, randomized, controlled, parallel, dietary intervention food study designed to examine the impact of pulse-enriched foods on cognitive function and cardiometabolic health in obese adults. Recruitment will consist of approximately 160 participants (n= 80 participants per site) at 2 sites located in Winnipeg and South Australia.

Participants will be randomly allocated to one of 2 groups; a pulse group or a control group. The pulse group will consume pulse-enriched foods designed to deliver ½ cup of pulses per day for 12 weeks. The control group will consume comparator foods for 12 weeks. The pulse and comparator food items will be provided to participants and they will be asked to incorporate these into their usual diet. Participants will be requested not to change their diet or physical activity habits during the study period, other than as required to comply with the study requirements. Five-day weighed food records will be completed during the week prior to baseline and during the final week of the study to monitor dietary intake, in particular intake of pulses. This will determine whether participants are incorporating the study foods as required, and will be used to evaluate associated changes in dietary intake and body weight, if they occur.

Inclusion criteria

• Male or females, between 50-80 years of age
• Body Mass Index (BMI) of >25 kg/m2
• Must be on a stable regime for the past 6 months if taking medications or supplements for elevated lipids, blood pressure, glucose management, mood, pain, or insomnia
• Consume 1 or less servings of pulses per week
• Able to read and understand English
• Willing to comply with the protocol requirements
• Willing to provide informed consent.

Exclusion criteria

• Body weight ≥135 kg (since this exceeds the capability for Dual Energy X-ray Absorptiometry, i.e, DEXA scanning to assess body composition)
• Established cardiovascular, liver, or kidney disease
• Uncontrolled diabetes (hemoglobin HbA1c >8)
• A score of ≤23 on the Mini Mental State Examination
• Use of appetite suppressants or Orlistat (Xenical)
• Inability to consume pulse-enriched foods (i.e., beans, peas, chickpeas, and lentils) due to allergies or severe gastrointestinal reactions
• Pregnancy
• Smoking or only recently quit smoking (smoked any cigarettes within the last 12 months)
• Weight loss of ≥3kg of body weight within the 6 months prior to enrolling in the study
• Adherence to a weight loss diet or physical activity program designed to facilitate weight loss
• Acute or terminal illness.