Uhmontpellier
Montpellier, 34295, France
NCT Number: NCT03698643
Transarterial chemoembolization (TACE) is the most performed endovascular interventional radiology (IR) procedure. TACE procedures are performed in an IR suite, most of which are equipped with floor-based flat-panel robotic C-arm allowing two-dimensional imaging. Cone-beam computed tomography (CBCT) has been developed to allow three-dimensional navigation but has several limitations such as reduced signal to noise ratio and small field-of-view, and seems to have negative impact on patient radiation exposure. Another option to perform 3D imaging is called angio-CT which combines a CT-scan and a floor-based flat-panel robotic C-arm in a single IR suite. Even if some publications have shown benefit of angio-CT in TACE procedures in Japan, no study about angio-CT in liver IR procedures has been conducted in the occidental world so far. The purpose of our study was to assess the impact of angio-CT use on patient radiation exposure and treatment quality in TACE procedures compared to CBCT.
This before-after study consisted of a review of consecutive TACE procedures performed between January 2016 and September 2017 in our institution with two different imaging modalities, defining two study groups (C-arm with CBCT versus angio-CT).
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Notify Me18 year and older
All sexes
Observational
Montpellier, 34295, France
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 1 day
Patient effective radiation dose (mSv) per TACE :
Dose-area product (in mGy/cm^2) and dose-length product (in mGy/cm) will be combined and converted to report effective dose (in mSv).
Time frame: 1 day
Air kerma (in mGy) per TACE
Time frame: 1 day
Fluoroscopy time (in sec) per TACE
Time frame: 1 day
Number of CBCT acquisitions per TACE
Time frame: 1 day
Number of CT acquisitions per TACE
Time frame: 1 day
Assessed on control CBCT or CT and graded into 3 classes : fully targeted, partially targeted or untargeted.
Time frame: 1 day
Assessed on follow-up CT or MRI and graded into 3 classes : response, tumor stability or progression.
University Hospital, Montpellier
Other
Impact of New Interventional Imaging Modality Use (Angio-CT) on Patient Radiation Exposure in Transarterial Chemoembolization
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