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NCT Number: NCT03976947

Impact of Lung Recruitment Maneuvers on Driving Pressure in Cardiac Surgery

In anesthesia the incidence of postoperative pulmonary complications is frequent, especially in cardiac surgery where the incidence can reach 10%. Respiratory morbidity in cardiac surgery is favored by multiple factors and is higher compared to anesthesia in "general" surgery. The prevention of these complications is a major challenge in the management of patients.

Influence of driving pressure level on respiratory morbidity was first demonstrated in management of acute respiratory distress syndrome (ARDS) in resuscitation.

More recently, this notion has been introduced in anesthesia, with a correlation between increase driving pressure level and increase of post-operative respiratory complications.

A method should reduce these levels of driving pressure: performing lung recruitment maneuvers. This technique has been successfully tested in abdominal surgery in particular in a study published by Futier et al.. They systematized and standardized lung recruitment maneuvers and showed a decrease of postoperative pulmonary complications in abdominal surgery.

Thus, the realization of lung recruitment maneuvers, already used at the discretion of the practitioner, is now recommended by several teams of experts. The investigators propose in this "before-after" trial to evaluate variation in driving pressure due to systematic use of lung recruitment maneuvers, observed in patients operated in elective or urgent surgery. The secondary objective is to evaluate their impact on postoperative pulmonary complications.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Caen University Hospital

Caen, 14000, France

About this study

This is a retrospective, before / after, monocentric trial.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients receiving elective or urgent cardiac surgery with cardiopulmonary bypass

Exclusion criteria

  • Emergency or salvage surgery
  • Patient under guardianship
  • Pregnancy

Treatment and study plan

Primary outcomes

  1. Driving pressure variation due to lung recruitment maneuvers

    Time frame: 1 day

    cmH2O

Secondary outcomes

  1. Incidence of postoperative pulmonary complications

    Time frame: baseline

    percentage

Sponsors and collaborators

Lead sponsor

University Hospital, Caen

Other

Registry information

Official study title

Impact of Lung Recruitment Maneuvers on Driving Pressure in Cardiac Surgery (IMPREMO): Before - After Trial

Acronym: IMPREMO

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jun 6, 2019
Registry last updated
Jan 21, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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