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OpenTrials
Completed

NCT Number: NCT06123208

Impact of Eating Beans on Metabolism

The purpose of this research is to test how eating a meal containing beans impacts how participants' bodies use food for energy.

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Key information

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

USDA Grand Forks Human Nutrition Research Center

Grand Forks, North Dakota, 58203, United States

About this study

The objective of this project is to test whether consuming a whole food that naturally contains resistant starch (RS), such as pulses, increases fat oxidation. The primary hypothesis is that consuming a RS-rich meal in which the RS is derived from a whole food (i.e., pinto beans, pinto bean flour) will increase postprandial fat oxidation to a greater extent than consuming a meal low in RS but containing the same amount of energy and macronutrient content.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI >18.5 or <30 kg/m2
  • Ability to understand and sign the consent form
  • Ability of transportation (i.e., participants must be able to provide their own transportation to the Grand Forks Human Nutrition Research Center)
  • Non-smoking or use of other tobacco products, including e-cigarettes
  • Not taking steroid-based medications; not planning to or currently attempting to gain or lose weight
  • All females of childbearing age must be on birth control for a minimum of 3 months prior to start of study

Exclusion criteria

  • Inability or unwillingness to consume any food item in the test meals
  • More than a 10% change in body weight within the past 2 months
  • Participation in a weight loss diet/exercise program
  • Current or planned pregnancy
  • Lactation
  • Uncontrolled hypertension (systolic >160 mmHg or diastolic >100 mmHg)
  • Diagnosed cardiovascular, pulmonary, skeletal and metabolic diseases
  • Fasting glucose > 100 mg/dL or non-fasting (1-2 hours after eating) >140 mg/dL
  • Using medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants)
  • Non-English speaking

Treatment and study plan

Whole cooked pinto bean

Other

Meal comprised of whole cooked pinto beans

Pinto bean flour

Other

Meal comprised of pinto bean flour

Control

Other

Control meal

Primary outcomes

  1. Acute effects of consuming processed pulse-based food products on substrate utilization

    Time frame: 5 hours after meal consumption

    The effect of consuming whole beans or bean-derived flour on the use of fat, carbohydrate, and protein for energy will be determine using whole room calorimetry. Fat, carbohydrate, and protein oxidation will be calculated as an absolute amount of grams per day and as a percentage of energy expenditure.

Sponsors and collaborators

Lead sponsor

USDA Grand Forks Human Nutrition Research Center

Fed

Registry information

Official study title

The Influence of the Resistant Starch and Protein Content of Pulses on Substrate Oxidation

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Nov 8, 2023
Registry last updated
Dec 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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