Groupe Hospitalier Pitié-Salpêtrière, Soins de Suite et Réadaptation
Paris, 75013, France
NCT Number: NCT03820843
A stroke located in the left parieto-temporal junction is associated, in aphasic right-handed patients, with a poor prognosis for language recovery. The role of the right hemisphere in recovering post-stroke aphasia is still controversial. Our hypothesis, based on recent work in imaging, is that early activation of the right hemisphere linked to the practice of the visual arts could facilitate language recovery in extended posterior left strokes that completely disrupt language areas.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Paris, 75013, France
The investigators will evaluate, at inclusion and at 6 weeks, the reorganization of functional and structural brain connectivity maps before and after rehabilitation of aphasia with art therapy and standard orthophonic rehabilitation versus a control group that received only standard orthophonic rehabilitation.
The investigators will include all consecutive patients with recent ischemic or hemorrhagic stroke with unilateral lesion(s) of the parieto-temporal left junction present on the Diffusion MRI (DWI) performed in acute phase at 24-48h.
All patients will undergo 2 MRI with tensor diffusion sequences (structural connectivity) and fMRI (functional magnetic resonance imaging) resting state sequences (functional connectivity) at inclusion and 6 weeks after rehabilitation with or without art therapy.
The investigators aimed to demonstrate that early activation of the right hemisphere related to the practice of the visual arts could facilitate the recovery of language in later strokes completely disrupting the language areas of the left hemisphere.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
In addition to standard orthophonic rehabilitation, the patient will receive 12 sessions of art therapy
Time frame: from inclusion at 6 weeks
Time frame: from inclusion at 6 weeks
Time frame: from inclusion at 6 weeks
The BDAE (Boston Diagnostic Aphasia Examination) score ranges from 0 to 5, with higher values indicating more severe impairment
Time frame: from inclusion at 6 weeks
The ART (Aphasia Rapid Test) score ranges from 0 to 26, with higher values indicating more severe impairment
Time frame: from inclusion and at 6 weeks
The HADS (Hospital Anxiety and Depression Scale) scores ranges from 0 to 21 for both anxiety and depression scores, with higher values indicating more severe impairment
Time frame: from inclusion at 6 weeks
Visual Analogic scale of patient quality of life is a 0% to 100% scale, with 100 indicating the best health status
Time frame: at 6 weeks only
visual analogic scale of patient satisfaction is a 0 to 10 scale, with higher values indicating better satisfaction
Assistance Publique - Hôpitaux de Paris
Other
Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia (ART-CONNECT)
Acronym: ART-CONNECT
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