Impact of Air Pollution and Climate Changes on the Epidemiology of Cardiovascular Disease

Despite the fact that the topic of air pollution has been in focus of researchers for many years, there are no big studies that take up the matter of its influence on acute coronary, cerebral syndromes and CVD mortality in Europe. Taking into consideration the scarce number of surveys from Europe the investigators decided to analyze the impact of air pollution on cardiovascular diseases and CVD mortality in Poland.

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Key information

Conditions

Pollution; Exposure Acute Coronary Syndrome Cardiovascular Diseases Cardiovascular Risk Factor Chronic Coronary Insufficiency Heart Diseases Myocardial Ischemia Particulate Matter Inhalation Injury Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Invasive Cardiology Medical University of Białystok 24A M. Skłodowskiej-Curie St.

Bialystok, 15-276, Poland

About this study

Air quality and its impact on health was put in the spotlight since the infamous Great Smog of London. Since then, it became clear that adverse effects are serious and can no longer be ignored. According to the World Health Organization (WHO) estimations, in last year ambient air pollution caused 4,200,000 deaths worldwide. These statistics included a total of 29,165 deaths that were attributed to air pollution in Poland.

The vast of studies are conducted in highly polluted areas, in which patients are exposed to extreme concentrations like China oraz Indie. Taking into consideration the scarce number of surveys from Europe the investigators decided to analyze the impact of air pollution and cardiovascular diseases in Poland.

Data on morbidity and mortality were collected from the National Statistical Office in Poland. The data of air pollutions and gases were obtained from Voivodeship Inspectorate for Environmental Protection. The daily meteorological data were obtained from the Institute of Meteorology and Water Manageme

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

residents from analysed area.

Exclusion criteria

none

Treatment and study plan

Impact of air pollution and climate changes

Other

To assess the short- and long- term impact of air pollution and climate changes

Primary outcomes

Incidence of acute coronary syndromes

Time frame: Through study completion, an average of 1 year

Number of acute coronary syndromes related with impact of air pollution
Incidence of cardiovascular mortality

Time frame: Through study completion, an average of 1 year

Number of cardiovascular deaths related with impact of air pollution
Incidence of acute cerebral syndromes

Time frame: Through study completion, an average of 1 year

Number of acute cerebral syndromes related with impact of air pollution

Sponsors and collaborators

Lead sponsor

Medical University of Bialystok

Other

Registry information

Acronym: PL-PARTICLES

Important dates

Study start: 2019
Primary completion: 2021
Study completion: 2022
First posted: Sep 9, 2020
Registry last updated: Jan 10, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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