Skip to main content
OpenTrials
Completed

NCT Number: NCT00702429

Immunoregulation of Periodontal Disease

Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Periodontal Disease Mouth Diseases Periodontal Diseases Stomatognathic Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hopital de la Conception- Laboratoire d'Immunologie

Marseille, 13274, France

About this study

These parameters will be measured in 25 healthy volunteers and 25 moderate-to severe periodontal disese patients. Phagocytes will be tested phenotypically and functionally, both ex vivo and in vitro.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Persons appearing spontaneously at the consultation of parodontologie for parodontale disease,
  • persons agreeing to undergo a sampling of blood intended for the search

Exclusion criteria

  • Presence of a chronic or pointed pathology,
  • an age 18-year-old subordinate or 65-year-old superior,
  • pregnant women,

Treatment and study plan

Blood sampling

Other

Analysis of the PNN, analysis of the monocytes

Primary outcomes

  1. Percentage of positive cells and intensity of expression for the molecules of surface studied there cytometric in stream

    Time frame: 24 months

Secondary outcomes

  1. Rate of secretion of cytokines and the other substances

    Time frame: 24 months

  2. Detection and quantification of ARN messengers

    Time frame: 24 months

Sponsors and collaborators

Lead sponsor

Assistance Publique Hopitaux De Marseille

Other

Registry information

Important dates

Study start
2008
Primary completion
2010
Study completion
2010
First posted
Jun 20, 2008
Registry last updated
Aug 28, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.