Immune Status of Elderly Population Admitted in an Acute Geriatric Unit

Ageing is associated with vulnerability against infections leading to increased morbidity with risk of death. Innate and adaptive immunities are altered with ageing responsible of deficits in immune response against pathogens and after vaccination, and favouring the elderly vulnerability against a new pathogen with increased bacterial, viral, and fungal infections.

If immunity has been widely studied in immunosenescence, there are few prospective, comparative studies with elderly ill patients. Moreover among these studies, pathologies are not well defined.

The main objective of our project is to compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects selected with strict criteria, in order to precise the impact of polypathology and of various pathologies on immunity state.

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Key information

Conditions

Aging

Age range

75 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

HOPITAL DE SAINTE MARGUERITE Service de Gériatrie Sud

Marseille, Paca, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Subject of 75 or more years old, female or male
Subject admitted in the service of short stay gériatrique of the hospital Holy Marguerite, whatever is the motive for admittance
Subject not being under supervision(guardianship), nor guardianship
Subject benefiting from a benefit system
Subject having given its assent of participation or for which the reliable person gave her assent in the case of vulnerable person

Exclusion criteria

Subject of less than 75 years old
Subject refusing to participate in the study or for whom(which) the reliable person refuses the participation of the subject

Treatment and study plan

Blood test and clinical test

Other

Blood test and clinical test

Primary outcomes

compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects

Time frame: 2 years

Sponsors and collaborators

Lead sponsor

Assistance Publique Hopitaux De Marseille

Other

Registry information

Important dates

Study start: 2009
Primary completion: 2012
Study completion: 2012
First posted: Jan 15, 2009
Registry last updated: Feb 25, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed