Skip to main content
OpenTrials
Completed

NCT Number: NCT01493362

Imaging the Dopamine Systems in Bulimia Nervosa

This study will use positron emission tomography imaging to investigate the dopamine systems in people with bulimia nervosa.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Eating Disorders Bulimia Nervosa Feeding and Eating Disorders Mental Disorders Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

New York State Psychiatric Institute

New York, 10032, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Participants with BN:

  • Meets DSM-IV criteria for BN
  • Sufficiently medically and psychiatrically stable to participate in research

Health Control Participants:

  • No current or past psychiatric illness
  • Between 80% and 120% of ideal body weight

Exclusion criteria

All participants:

  • Current use of psychotropic medication such as anti psychotics or antidepressants
  • Pregnant or breastfeeding
  • history of substance abuse
  • Significant medical illness
  • High blood pressure (resting systolic blood pressure greater than 150mmHg and diastolic blood pressure greater that 90 mmHg)
  • Current or lifetime history of schizophrenia, bipolar disorder, or other psychotic disorder as defined by DSM-IV
  • Metal implants or paramagnetic objects contained within the body that may interfere with the MRI scan, as determined in consultation with a neuroradiologist and according to specified reference book guidelines
  • Exposed to radiation in the workplace or has had a nuclear medicine procedure during the 1 year before study entry
  • Previous adverse reaction to psycho stimulants

Treatment and study plan

Primary outcomes

  1. D2 receptor density

    Time frame: Measured at baseline

  2. DA release in the striatum

    Time frame: Measures after Mythlyphenidate challenge

Sponsors and collaborators

Lead sponsor

New York State Psychiatric Institute

Other

Collaborators

  • National Institute of Mental Health (NIMH)

Registry information

Important dates

Study start
2008
Primary completion
2013
Study completion
2013
First posted
Dec 16, 2011
Registry last updated
Aug 15, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.