Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07707570

Hysteroscopic Findings With Histopathologic Report of Endometrium in Patients With Postmenopausal Bleeding

To evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium., Sohag University Hospital Obstetrics and Gynecology department

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

45 year and older

Sex eligibility

Female

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Postmenopausal women presenting with uterine bleeding
  • Age ≥ 45 years

*Exclusion criteria:

  • Women on hormone replacement therapy
  • Bleeding due to vulvar, vaginal, cervical, or urethral causes
  • Patients on anticoagulant therapy
  • Patients unfit for hysteroscopy
  • Refusal to participate

Treatment and study plan

Primary outcomes

  1. evaluate hysteroscopic findings in women with postmenopausal bleeding and correlate them with histopathological results of the endometrium

    Time frame: 2 weeks

    All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet).

    I. Clinical Assessment

    • Detailed history including:
    • Duration since menopause
    • Pattern and duration of bleeding
    • Obstetric and medical history
    • General abdominal and pelvic examination

    II. Transvaginal Ultrasound (TVS)

    • Measurement of endometrial thickness
    • Assessment of uterine and adnexal pathology

    III. Hysteroscopic Examination

    Hysteroscopy will be performed using a rigid hysteroscope to evaluate:

    • Endometrial appearance
    • Presence of polyps, hyperplasia, or malignancy

    Hysteroscopic findings will be classified as:

    • Normal (proliferative, secretory, atrophic)
    • Abnormal (polyp, hyperplasia, carcinoma, fibroid) (1,3)

    Criteria suggestive of:

    • Hyperplasia: irregular thickened endometrium, increased vascularity (1,3)
    • Carcinoma: irregular necrotic tissue, atypical vessels, friable surface (1,3)

    IV. Endometrial Sampling

    • Directed biopsy will be taken from s

Study contacts

Contact information is provided by the study sponsor or research team.

Mahmoud Sabri Mahmoud Mohamed Sabri Mahmoud, Resident

CONTACT

[email protected]

01001264613

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Evaluation of Hysteroscopic Findings With Histopathologic Report of Endometrium in Patients With Postmenopausal Bleeding

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jul 16, 2026
Registry last updated
Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.