Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07581743

How Can Different Forms of Strengthening Exercises Affect the Muscular Tissue and Its Chemical Markers in Children With Duchenne Muscular Dystrophy

The treatment of patients diagnosed with DMD needs to be multidisciplinary, judicious, and always focused on the patient's well-being. Physiotherapy and occupational therapy are very often standard care. Physiotherapy is regarded as crucial for the success of treatment, since it has achieved good results in the short term, such as maintaining the autonomy of these individuals . Physical activity is another method that has been used to treat DMD. Studies have used physical exercise in individuals with DMD in order to decrease muscle deterioration, muscle contractures, and bone fractures, and to increase the time of functional independence

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Duchene Muscular Dystrophy

Age range

6 year–10 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Reham

Giza, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • DD,
  • aging from 6 To 10

Exclusion criteria

  • able to understand order

Treatment and study plan

Strengthening Exercises

Other

Concentric strengthening exercises: involves the muscle producing tension and shortening to move a load Isometric strengthening exercises: occurs when a muscle produces tension without a change in muscle length. Isometric contractions involve sarcomere shortening and increasing muscle tension, but do not move a load Eccentric strengthening exercises: occurs when the muscle tension produced is less than the load and a muscle lengthens while under tension

Low-Intensity Exercise Protocol

Other

The children were trained 3 times per week for 8 weeks on a treadmill without inclination, with speed and time programmed and adapted for this purpose. The length of each training activity was 30 min (Andersen et al. 2013; Markert et al. 2012). The children were acclimated to the treadmill for 7 days before the beginning of the training program, with a speed of 4 m/min, in order to minimize the stress caused by the different environment.

Traditional physical therapy program

Other

traditional physical therapy program to improve strength

Primary outcomes

  1. Creatine-kinase (CK)

    Time frame: 8 weeks

  2. Six-minute walk test

    Time frame: 8 weeks

  3. Muscle strength

    Time frame: 8 weeks

Study contacts

Contact information is provided by the study sponsor or research team.

Reham Alsakhawi

CONTACT

[email protected]

00966504182628

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Different Forms of Strengthening Exercises and Chemical Markers in Children With Duchenne Muscular Dystrophy

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 12, 2026
Registry last updated
May 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.