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NCT Number: NCT05563363

Home Treatment for Individuals Suffering From Severe Addictive Disorders

Home Treatment (HT) has been successfully implemented in adult psychiatry in several countries including Switzerland. Patients with addiction problems were generally excluded even if the latter was not the main diagnosis. On the other hand, community treatments have successfully been established for these individuals. The investigators have recently offered HT to persons with severe addictive disorders which was well accepted.

The investigators intend to conduct a pilot study to prepare a large-scale study if successful. The investigators intend to compare HT to treatment as usual (regular inpatient treatment) on a specialized ward with respect to readmission rates during 6 months after discharge. The data show that 70.8% of all readmissions occur during the first 6 months. Therefore, a period of 6 months is considered an adequate time interval to sufficiently answer this pilot study's question.

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Key information

Conditions

Substance Use Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Geneva University Hospital

Geneva, Switzerland

Location status: Recruiting

Location contact

Louise Penzenstadler, MD

CONTACT

[email protected]

+41223725750

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Substance use disorder
  • age 18 or above
  • sufficient french language skills
  • competent subjects
  • consent to randomization progress

Exclusion criteria

  • organic brain disease or developmental disorder
  • non voluntary admission
  • severe somatic comorbidity
  • History of complicated substance withdrawal
  • acute suicidal ideation
  • aggressive behavior
  • acute psychiatric disease such as mania or psychosis
  • distance to center (must be reachable within 60 minutes)

Treatment and study plan

Hospital-like treatment in patients' home

Other

Hospital-like treatment in patients' home. Caregivers, medical doctors and social workers will make several visits per day to the patients' home. 24/7 contact is available.

standard inpatient treatment

Other

Inpatient treatment on addiction ward

Primary outcomes

  1. readmission rates

    Time frame: 6 month post-discharge

    Number of readmissions to hospital during the 6 months following discharge

Secondary outcomes

  1. time to readmission

    Time frame: 6 months

    Number of days between discharge and readmission during the 6 months following discharge

  2. length of hospitalization

    Time frame: 6 months

    total number of days spent in hospital during the 6 months following discharge

  3. number of emergency room visits

    Time frame: 6 months

    number of emergency room visits during the 6 months following discharge

  4. clinical outcome

    Time frame: 6 months

    clinical outcomes measured with Health of the Nation Outcome scale (HoNOS) scoring 0 (no symptoms) to 48 (high symptom level) and the Brief Symptom Check-List (short form of the Brief Symptom Inventory), scoring 0-53 items (higher score = more symptoms). Measured at the start and end of intervention/hospital treatment.

  5. patient satisfaction

    Time frame: 6 months

    Patient satisfaction measured with the S-ANQ (https://www.anq.ch/en/), a questionnaire used by all Swiss hospitals to measure patient satisfaction with treatment. The questionnaire includes 6 questions which are marked from 0 not at all satisfied to 5 = very satisfied. Scoring 0 (not at all satisfied) to 30 (very satisfied)

Study contacts

Contact information is provided by the study sponsor or research team.

Louise Penzenstadler, MD

CONTACT

[email protected]

+41223725750

Sponsors and collaborators

Lead sponsor

Louise Penzenstadler

Other

Registry information

Official study title

A Pilot Study on Home Treatment for Individuals Suffering From Severe Addictive Disorders

Important dates

Study start
2022
Primary completion
2025
Study completion
2026
First posted
Oct 3, 2022
Registry last updated
Aug 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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