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Completed

NCT Number: NCT06862505

Histological Analysis of Peri-implant Soft Tissue

The aim of this study is to evaluate the histologically analysis in humans and the orientation of collagen fibers around screw-less, morse taper implant-abutment connection.

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Key information

Conditions

Implant Therapy Biological Width

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

University of Rome

Rome, Italy

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years or older, affected by partial edentulism of posterior elements need for at least two single implant rehabilitations
  • able to understand a sign an informed consent

Exclusion criteria

  • Peapole having a systemic or local contraindications for implant placement;
  • Untreated periodontal disease;
  • smokers;
  • osteoporosis;
  • uncontrolled diabetes;
  • refusal to implant rehabilitation;
  • refusal to biopsy collection;
  • systemic pathologies that could compromise the healing of peri-implant tissues.

Treatment and study plan

Biopsy

Procedure

Biopsy of soft tissue were taken randomly at 8 or 16 weeks to compare soft tissue

Primary outcomes

  1. Histological analisys

    Time frame: 8 and 16 weeks

    Histological analysis of peri-implant gengivaat 8 and 16 weeks to assess collagen fibre orientation

Secondary outcomes

  1. Histomorphometry

    Time frame: 8 and 16 weeks

    Quantitative measure of soft tissues

Sponsors and collaborators

Lead sponsor

Università degli Studi di Sassari

Other

Registry information

Official study title

Histological Analysis of Collagen Fibers Around Screw-less, Morse Taper Implant-abutment Connection 8 and 16 Weeks After Implant Uncovering: a Split-mouth Randomized Controlled Trial

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Mar 6, 2025
Registry last updated
Mar 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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