High-resolution CE-MRA of Children's Hip Joint

The goal of this observational study is to learn about the feasibility of enhanced three-dimensional water-selective cartilage (3D-WATSc) sequence in displaying the vessels of children's hip by magnetic resonance. The main questions it aims to answer are:

* Could the images of enhanced 3D-WATSc sequence show the healthy side hip joint vessels in children? * Could the images of enhanced 3D-WATSc sequence show the vascular disease of the suffering side hip joint in children?

Participants with unilateral hip disease will undergo the magnetic resonance examination including enhanced 3D-WATSc sequence. The pelvic plain film and magnetic resonance images will be collected and analysed.

Researchers will compare the images of of the normal side with the images of the abnormal side to see if the enhanced 3D-WATSc sequence images could show the vascular disease of the suffering side hip joint in children?

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Key information

Conditions

Hip Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Magnetic Resonance Three-dimensional Water-selective Cartilage (3D-WATSc) Vessels; Anomaly

Age range

6 month–14 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Children's Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400014, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Children aged 6 months-14 years who are diagnosed as hip disease after screening by pediatric orthopedic surgeon in Children's Hospital of Chongqing Medical University during the study period. The hip disease contain developmental dysplasia of the hip, Perthes disease, infection of the hip, inflammation of the hip, fracture of the hip, and Meyer's dysplasia.

Exclusion criteria

patients with bilateral hip joint disease; patients with claustrophobia;Patients with metal implants (such as pacemaker implantation)

Treatment and study plan

Magnetic resonance examination

Other

the two groups are underwent magnetic resonance examination including enhanced 3D-WATSc sequence

Primary outcomes

The medial circumflex femoral artery (MCFA) and lateral circumflex femoral artery (LCFA) of the bilateral hip joint

Time frame: 1 day (Magnetic resonance examination end time)

Morphology of the MCFA and LCFA of the bilateral hip joint
The branches of the MCFA and/or LCFA around the bilateral femoral neck

Time frame: 1 day (Magnetic resonance examination end time)

Morphology of MCFA and/or LCFA branches around the bilateral femoral neck
The vessels of secondary ossification center and/or cartilaginous vascular canal in bilateral femoral head

Time frame: 1 day (Magnetic resonance examination end time)

Morphology of the vessels and cartilaginous vascular canal in bilateral femoral head

Sponsors and collaborators

Lead sponsor

Children's Hospital of Chongqing Medical University

Other

Registry information

Official study title

High-resolution Contrast-enhanced Magnetic Mesonance Angiography of Children's Hip Joint

Important dates

Study start: 2021
Primary completion: 2022
Study completion: 2023
First posted: Mar 6, 2023
Registry last updated: Mar 6, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed