Skip to main content
OpenTrials
Completed

NCT Number: NCT04950062

High Intensity Interval Training Versus Intermittent Fasting on Functional Capacity Among Overweight Subjects

The purpose of the study is to compare the effect of high-intensity interval training and intermittent fasting on improving body weight and functional capacity among overweight subjects.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Overweight Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

25 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Outpatient clinic - Faculty of Physical Therapy - Horus University

Damietta, 34518, Egypt

About this study

Exercise improves cardiorespiratory fitness, muscle strength, endurance, body composition, and decreases visceral fat. The, increase in physical activity and modification of eating behaviors are the first line of interventions given because of their low costs and low risks of complications.

Most commonly, the continuous exercise of moderate intensity, that has to be performed several days of the week to get target benefits have been used, on the other hand, different forms of training which aim to reduce time spent exercising by increasing exercise intensity have been considered as an alternative to increasing adherence to the training program which is supported by some researches that may have greater benefits as high intensity interval training improves the vascular function of the muscle capillary density and endothelial nitric oxide synthase(eNOS) levels. But there are some overweight people even some of the young people have restriction to perform exercise programs due to any medical problem that could interfere with exercise.

So, searching for optimal dietary interventions for obesity is still ongoing, but the modification in eating behaviors are hampered by difficulties in coping with a different diet. So, the diet with a fasting component that will be used in this study may be more effective than other complex and restrictive diets as it essentially limits the caloric intake to a specified period without major diet composition changes.

So, the aim of this study is to compare the effect of high-intensity interval training and intermittent fasting on improving body weight and functional capacity among overweight subjects.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects have to meet all the following criteria in order to participate in the study:
  • Overweight subjects with age from 25 to 35 years.
  • Body mass index will be range from 25 to 29.9 kg/m2.
  • Waist circumference ≥ 80 cm2.
  • A minimum of 70% of exercise program and diet regimen compliance will be required in order to be included.

Exclusion criteria

  • Subjects with the following disorders will be excluded from participating in this study:
  • Musculoskeletal, cardiovascular disorders.
  • Asthma, chronic obstructive pulmonary diseases.
  • Any systemic disease or condition that might reduce adherence or tolerance to exercise or fasting.
  • History of stroke.

Treatment and study plan

High Intensity Interval Training

Other
  • Warming up period for 5 min at an intensity corresponding to 65-75% of heart rate maximum (HRmax).
  • Training phase for 30 min divided into four sets of 4-min length each at intensity equals 80-90% of HRmax interspersed by 3 minutes low intensity walking at the level of 65-75% of HRmax.
  • Cooling down period for 5 min of at 50-60% of the HRmax. All subjects will be trained at the lower intensity limit for the first 2 weeks of the program before increasing the intensity levels toward the upper limit.

Intermittent Fasting 16/8 Protocol

Other

Every subject will be instructed to fast a fixed 16 hours followed by 8 hours of eating every day through the whole study period based on their life and sleeping style. During fasting, zero-calorie coffee, tea and water intake will be permitted. Beverages containing calories were consumed during the feeding hours each day. All subjects will be instructed about their optimum caloric requirement based on their basal metabolic rate that will be calculated in advance to avoid over consumption of food on severe caloric restriction as we like to investigate the effect of this way of fasting on reducing weight and improving functional capacity.

Primary outcomes

  1. Assessing the change in Vo2max

    Time frame: Baseline and 2 months post-intervention

    Assessment via using Standard Bruce protocol will be used to measure (VO2) max. The Bruce protocol for multi stage treadmill testing of maximal exercise will be used. This will begin with stage 1 with walking slowly for three minutes at 2.7 Km/hr at a 10% grade (inclination), speed and grade then increased in every stage of 3 minutes and end at stage 7 or till exhaustion.

  2. Assessing the change in body weight

    Time frame: Baseline and 2 months post-intervention

    Assessment via using of body weight scale with height (m) scale to be able to calculate body weight (Kg).

  3. Assessing the change in waist hip circumference

    Time frame: Baseline and 2 months post-intervention

    Assessment via using Tape measures It will be used to measure waist and hip circumference and calculate waist hip ratio

Sponsors and collaborators

Lead sponsor

Horus University

Other

Registry information

Official study title

Effect of High Intensity Interval Training Versus Intermittent Fasting 16/8 Protocol on Functional Capacity Among Overweight Subjects

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jul 6, 2021
Registry last updated
Jul 6, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.