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NCT Number: NCT06914336

Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation (DOHECOV)

The purpose of the study is to investigate venous congestion using hepatic vein doppler for ICU patients with invasive mechanical ventilastion. The primary outcome is the systolic to diastolic hepatic vein velocity ratio S/D . The objective is to find a significant association between S/D and different congestion indicators.

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Key information

Conditions

Congestion, Venous Cardiovascular Diseases Hyperemia Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • intubated for more than 24 hours

Exclusion criteria

  • Chronic end-stage renal disease on admission
  • Atrial Fibrillation
  • Cirrhosis
  • Portal thrombosis
  • Refusal to participate
  • non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity
  • Under legal protection.

Treatment and study plan

Primary outcomes

  1. Systolic to diastolic hepatic vein velocity ratio S/D

    Time frame: 24 hours after intubation and after every 48 hours until extubation up to 12 weeks

    Relate S/D ratio to clinical data on venous congestion: input/output balance, weight variation, renal insufficiency, diuresis, edema.

Study contacts

Contact information is provided by the study sponsor or research team.

Gwenael PRAT, phD

CONTACT

[email protected]

0298347181 ext. +33

Hamza CHRAIBI, phD

CONTACT

[email protected]

0298347181 ext. +33

Sponsors and collaborators

Lead sponsor

University Hospital, Brest

Other

Registry information

Official study title

Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation

Acronym: DOHECOV

Important dates

Study start
2025
Primary completion
2028
Study completion
2028
First posted
Apr 6, 2025
Registry last updated
Apr 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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