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Completed

NCT Number: NCT02374762

Hemodialysis Vascular Access Imaging Study

The goal of this study is to find the best techniques to take non-invasive images of the arteriovenous fistula (AVF) in hemodialysis patients.

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Key information

About this study

The vascular access is at the same time both the 'lifeline' and the 'Achilles' heel' of hemodialysis patients. Despite improved understanding of the pathophysiology of stenosis and thrombosis of the vascular access, unfortunately translating these advances into either improved therapies or a superior process of care has not been very successful. As a result, there continues to be an epidemic of arteriovenous fistula (AVF) maturation failure, a proliferation of relatively ineffective interventions such as angioplasty and stent placement, an extremely high incidence of catheter use (1).

A major problem is the timely diagnosis of AVF access dysfunction, which - undiagnosed and untreated - will eventually result in its loss. Current methods of diagnosing impending AVF deterioration utilize measurement of access flow, access flow recirculation, ultrasound imaging and angiography. None of these methods are applicable on a per-treatment basis and require some sort of intervention.

Recent advances in video-imaging open the opportunity to non-invasively track AVF movements, possibly on a routine basis. These AVF movements are created by the arterial pulse and routinely checked manually prior to each AVF cannulation. In this research the investigators plan to film the actual AVF movements with the goal to explore the technical feasibility of video-imaging based access surveillance.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age > 18 years; routinely cannulated AVF in place

Exclusion criteria

  • inability to communicate in English
  • skin maladies which render meaningful AVF imaging impossible
  • vascular access procedures in the last 8 weeks

Treatment and study plan

Primary outcomes

  1. Images of Arteriovenous fistula (AVF) Thrill

    Time frame: 6 months

    To determine if optimized video images can show the movements of the AVF pulse.

Sponsors and collaborators

Lead sponsor

Renal Research Institute

Other

Registry information

Official study title

Contact-Free Video Imaging of Arteriovenous Fistulas In Chronic Hemodialysis Patients

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Mar 2, 2015
Registry last updated
Feb 24, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.