Trinity Western Unversity
Langley, British Columbia, V2Y 1Y1, Canada
Location status: Recruiting
NCT Number: NCT06551168
Heat acclimation is when you repeatedly exposure yourself to heat so that your body adapts and better tolerates heat.
This project will determine if completing a heat acclimation maintenance period after heat acclimation is more beneficial than heat acclimating alone for exercise performance in the heat. To determine this, participants will exercise in the heat before heat acclimation, after heat acclimation, and after heat acclimation maintenance. Researchers will assess the heart's pumping capacity, blood volume, body temperature, and exercise performance to determine which approach is more effective.
Interested in participating?
Request Info18 year–55 year
Female
Interventional
Not applicable
Langley, British Columbia, V2Y 1Y1, Canada
Location status: Recruiting
Purpose and Hypothesis: Global warming combined with increased frequency of heat waves exposes those who are working, exercising, or competing outdoors to considerable thermal strain. Excessive heat stress decreases exercise performance and can lead to heat illnesses. Deliberate serial exposure to natural (acclimatization) or artificial (acclimation) heat (HA) is the most efficacious method to defend homeostasis at rest and during exercise in hot environments. Our project will determine if three weeks of heat acclimation maintenance (HAM) further potentiates exercise performance in the heat than exercise performance measured after 10 days of HA in females.
Justification: Female participation in arduous occupations and professional sport is increasing. Presently a paucity of data regarding the female response to heat acclimation exist. Findings from this study will help females undertake effective and efficient strategies to mitigate thermal strain.
Research design: This is an experimental trial with a treatment and a control group. VO2max, plasma volume (PV), core temperature, and cardiac output will be measured pre-, mid-, and post-intervention. Participants will complete 10 sessions of HA over two weeks. Participants will then undergo three weeks of HAM with three heat sessions per week. A heat performance test will be completed pre-, mid-, and post-intervention to examine performance changes. A control group will complete the same test schedule but will not perform any HA or HAM.
Statistical analysis: Sample size will be 8 females in the experimental and 6 females in the control group. Data will be analyzed for normality using the Shapiro-Wilk test. Descriptive statistics will be presented as the mean and standard deviation. Statistical significance will be determined at P <0.05. A two-way repeated measure ANOVA will be used to measure differences between groups and hemodynamic, cardiovascular and performance variable differences pre- and post-HA, and pre- post-HAM. If significant effects are present, these will be followed by a post-hoc Tukey's test. Pearson's r correlations (two-tailed) will be conducted between VO2max, and intravascular volumes and heat performance test outcome.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants will exercise at home while wearing a clothing ensemble over 19 one hour sessions. They will use validated perceptual scales to guide their effort and thermal sensation.
Participants will exercise at home over 19 one hour sessions. They will use heart rate to guide their effort. The exercise will take place in cool conditions
Time frame: 2 weeks and 5 weeks
Participants will complete a timetrial on a cycle ergometer in a heat chamber. Faster times following HA or HAM will be considered a marker of performance
Time frame: 2 weeks and 5 weeks
Expanded plasma volume or increased hemoglobin mass will be considered a positive response to heat acclimation
Contact information is provided by the study sponsor or research team.
Anita T Coté, PhD
CONTACT
604.513.2121 ext. 3726
Normand A Richard, MSc
CONTACT
604.513.2121 ext. 3726
Trinity Western University
Other
The Cardiovascular, Hematological, and Performance Response to Heat Acclimation in Healthy Trained Females
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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