Heart Rate Sensing and Response in Persons With Anorexia Nervosa

The purpose of this pilot investigation is to assess AN interoceptive sensitivity and responsivity as it pertains to heart rate during exercise. Thirty adults, 18 years and older will be recruited for a cross-sectional comparison of IS and IR in the context of exercise.

Inclusion criteria

Study participants will include adults with anorexia spectrum disorders and healthy age and gender matched controls. There will be two control groups, one that includes regularly exercising age and gender matched persons and one where controls do not engage in regular exercise.

For those with AN, the following INCLUSION criteria must be met:

• Age ≥ 18 years old
• BMI 25 kg/m2 or less
• Diagnosis of anorexia spectrum disorder
• Medications: Stable use of all medications ≥ three months

For age and gender matched controls, the following INCLUSION criteria must be met:

• Age ≥ 18 years old
• BMI 25 kg/m2 or less
• No diagnosis of anorexia spectrum disorder
• Medications: Stable use of all medications ≥ three months
• Age (+/- 2 years) and gender matched to study participant

Exclusion criteria

• History of diabetes, heart disease or taking medications for those conditions
• History of hypertension (high blood pressure) not controlled with medication
• Orthopedic limitations, musculoskeletal disease and/or injury
• Inability to consent
• Lack of transportation to the Duke Center for Living campus