Health eHeart BioBank

The purpose of the Health eHeart BioBank is to collect and store specimen (e.g. blood, DNA, tissue) for future studies at the University of California, San Francisco (UCSF) that will help determine changes and identify molecular and genetic markers in the human body that might help increase our knowledge of heart disease and guide development of new diagnostic tools and treatments that may help rapidly detect heart disease and prevent and/or treat heart disease.

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Key information

Conditions

Heart Diseases Cardiac Diseases Cardiovascular Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of California, San Francisco

San Francisco, California, 94158, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age ≥ 18 years or older.

And at least one of the following:

Established patient seen at UCSF and/or is a current participant in a clinical study that utilizes the HeH BioBank for biospecimen collection.
Family member of a patient with cardiovascular disease.
Patient with no cardiovascular disease.

Exclusion criteria

Unwilling to consent to biospecimen collection through the HeH BioBank.

Treatment and study plan

Blood draw

Procedure

Participants will be asked to contribute approximately 36 mL of blood using standard procedures and obtained at the time of a clinically ordered routine blood draw or a study ordered blood draw. Participants may be asked to contribute additional blood samples over the course of their participation in the study.

Tissue collection

Procedure

If the participant is undergoing a clinically ordered procedure (e.g. heart surgery/biopsy/transplant), then they will be asked to contribute tissue to the study before any tissue is collected during the procedure. Most samples collected by the HeH BioBank will be tissue that would be normally discarded after the procedure.

DNA collection

Procedure

Participants will be asked to contribute their DNA for Whole Genome Sequencing (WGS) to help identify genetic markers of heart disease. DNA will be obtained at the time of the blood draw or obtained through DNA collection kits administered to participants who are unable or unwilling to undergo a blood draw.

medical chart review

Other

Demographic, clinical, and pathologic information will be extracted from the participant's medical record.

Other names: Medical Record Review

Primary outcomes

Establish and Maintain a Centralized Biorepository

Time frame: Up to 10 years

Establish and maintain a centralized biorepository to collect and store a variety of biospecimen samples and clinical data.

This would allow for the samples and clinical data to be used to test hypotheses regarding the molecular and genetic basis of diagnosis and treatment of cardiovascular diseases.

Sponsors and collaborators

Lead sponsor

University of California, San Francisco

Other

Registry information

Acronym: HeH BioBank

Important dates

Study start: 2025
Primary completion: 2035
Study completion: 2035
First posted: May 16, 2025
Registry last updated: Jul 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting