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NCT Number: NCT07006909

Hair Isotope Analysis for Early Cancer Detection

Cancer is a major health challenge, and early detection is crucial for improving patient outcomes. Research has shown that cancer can alter the way the body processes nutrients. This study aims to explore whether these metabolic changes can be detected through a simple, non-invasive method: analysing hair. Hair grows slowly over time, potentially capturing subtle metabolic changes that occur during cancer development. By studying the nitrogen stable isotope composition in hair samples donated by individuals diagnosed with cancer, we aim to identify potential early markers of the disease. Participants will be asked to donate a small strand of hair, which will be analysed using a laboratory technique called Isotope Ratio Mass Spectrometry (IRMS). The findings from this study could contribute to new, non-invasive screening tools for early cancer detection.

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Reading

Reading, RG6 6DZ, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Cancer diagnosis, sufficient hair

Exclusion criteria

-

Treatment and study plan

Primary outcomes

  1. longitudinal changes in d15N in hair

    Time frame: Approximately one year

    Longitudinal changes in d15N in hair samples to obtain a time-series

Study contacts

Contact information is provided by the study sponsor or research team.

Gunter GC Kuhnle, Doctor rerum naturalium

CONTACT

[email protected]

+44 118 3787723

Sponsors and collaborators

Lead sponsor

University of Reading

Other

Registry information

Acronym: HI-CARE

Important dates

Study start
2025
Primary completion
2030
Study completion
2030
First posted
Jun 5, 2025
Registry last updated
Jun 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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