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OpenTrials
Completed

NCT Number: NCT07306377

H. Pylori Infection and AIP Levels

Helicobacter pylori is a common bacterial infection of the stomach that can cause ulcers and other digestive problems. Recent studies suggest that this infection may also affect metabolism and blood fats (lipids), which are important for heart health. Changes in lipid levels, such as higher triglycerides and lower "good" cholesterol (HDL), can increase the risk of cardiovascular disease.

This study will examine whether H. pylori infection is linked to changes in lipid profiles, especially the Atherogenic Index of Plasma (AIP). AIP is a calculation based on triglycerides and HDL cholesterol that helps predict the risk of heart disease.

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Key information

Conditions

H Pylori Infection Atherogenic Plasma Index

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine

Tanta, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients older than 18 years.
  • Able to sign the written consent.
  • Willing to participate in the research and undergo H. pylori testing. Exclusion criteria
  • Unwilling to participate in the study.
  • History of severe metabolic disorders.
  • Taking medications that affect adipose tissue metabolism.
  • History of gastric surgery.

Treatment and study plan

urea breath test

Diagnostic Test

Participants will undergo a urea breath test to confirm H. pylori infection status.

Fasting blood samples will be collected to measure triglycerides and HDL cholesterol, and the Atherogenic Index of Plasma (AIP) will be calculated.

Primary outcomes

  1. Atherogenic Index of Plasma (AIP)

    Time frame: Baseline (single fasting blood sample at enrollment).

    AIP is calculated as log10(triglycerides/HDL cholesterol).

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Helicobacter Pylori Infection as A Potential Risk Factor for Dyslipidemia: Insights From Atherogenic Index of Plasma (AIP)

Acronym: HP-AIP

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Dec 29, 2025
Registry last updated
Dec 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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