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Completed

NCT Number: NCT07150533

Green Tea Extract and Ginger

This study investigates the effects of green tea extract and ginger supplementation, both individually and in combination, on endurance performance, metabolism, thermal comfort, and muscle soreness in recreationally active young men. Participants will complete cycling tests under both normal room temperature (21-24°C) and cold (5-7°C) conditions. The study uses a randomized, double-blind, placebo-controlled, crossover design to compare the outcomes of placebo, green tea, ginger, and combined supplementation. The findings may help to identify nutritional strategies that improve exercise performance and comfort in different environmental conditions.

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Key information

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Erzurum Technical University Sport Sciences Faculty

Erzurum, 25240, Turkey (Türkiye)

About this study

This randomized, double-blind, placebo-controlled, crossover trial is designed to evaluate the effects of green tea extract and ginger supplementation, both individually and in combination, on endurance performance, metabolic responses, thermal sensation, and muscle soreness in recreationally active men.

Sixteen healthy participants will complete eight experimental conditions: placebo, green tea extract (500 mg), ginger (1 g), and a combination of both, tested under normal (21-24°C) and cold (5-7°C) environments. Each condition will be separated by a washout period to avoid carryover effects.

Endurance capacity will be measured using a time-to-exhaustion cycling test at 70% of maximal oxygen uptake (VO₂max). Metabolic responses will be assessed by gas analysis to determine respiratory exchange ratio (RER). Perceptual measures will include the Borg Rating of Perceived Exertion (RPE) and a thermal sensation scale, while muscle soreness will be evaluated 24 hours post-exercise using a visual analog scale (VAS).

The study aims to determine whether the combined intake of green tea and ginger provides synergistic benefits over individual supplementation, particularly in cold environments where thermoregulation and endurance capacity are challenged. Findings may contribute to practical nutritional strategies that enhance exercise performance, comfort, and recovery under environmental stress conditions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male participants aged 18-35 years

Recreationally active (≥3 aerobic exercise sessions per week, ≥30 minutes per session, for at least 6 months)

VO₂max between 40-50 mL/kg/min (recreationally active fitness level)

Body mass index within the normal to slightly overweight range (approximately 18.5-27.5 kg/m²)

Willingness to comply with study requirements, including supplementation and exercise testing protocols

Provided written informed consent

Exclusion criteria

History of cardiovascular, respiratory, metabolic, or neurological disorders

Allergy or intolerance to green tea, ginger, or maltodextrin

Current use of ergogenic supplements, medications affecting metabolism, or stimulants (e.g., beta-blockers, caffeine pills)

Smoking or excessive alcohol consumption (>14 units per week)

Inconsistent exercise habits (<3 sessions/week in the past 6 months)

Participation in another clinical trial within the past 3 months

Treatment and study plan

Placebo Arm

Dietary Supplement

Participants receive a placebo consisting of maltodextrin in capsule form, matched in appearance and taste to the active supplements.

Green Tea Extract

Dietary Supplement

Participants receive 500 mg of standardized green tea extract in capsule form.

Ginger

Dietary Supplement

Participants receive 1 g of ginger supplement in capsule form.

Combined Supplement (Green Tea + Ginger)

Dietary Supplement

Participants receive a combination of 500 mg green tea extract and 1 g ginger, both administered in capsule form.

Primary outcomes

  1. Time to Exhaustion (TTE)

    Time frame: Immediately during each exercise test session (after supplement ingestion, under normal and cold environmental conditions)

    Endurance performance assessed as the total time in seconds participants are able to maintain cycling at 70% of VO₂max on a cycle ergometer, until volitional exhaustion defined as the inability to sustain a cadence of 60 rpm for 10 consecutive seconds

Sponsors and collaborators

Lead sponsor

Erzurum Technical University

Other

Registry information

Official study title

Synergistic Effects of Green Tea Extract and Ginger Supplementation on Endurance Performance and Thermal Perception in Normal and Cold Environments: A Randomized Crossover Trial

Acronym: Thermal effect

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 2, 2025
Registry last updated
Sep 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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