Skip to main content
OpenTrials
Completed

NCT Number: NCT06121037

Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach)

Combined migraine and cervicogenic headache present significant challenges in clinical management due to their complex and overlapping pathophysiologies. Both conditions involve the trigeminocervical complex, suggesting a potential shared anatomical and neurobiological basis

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Greater Occipital Nerve Pulsed Radiofrequency

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Assiut governorate

Asyut, 715715, Egypt

About this study

Traditional treatment approaches for these headaches often include pharmacological interventions, but in cases of refractory or inadequate response, interventional techniques targeting the greater occipital nerve (GON) have gained attention.

Radiofrequency ablation (RFA) has gained recognition as a potential therapeutic option for patients with refractory combined migraine and cervicogenic headaches. The proximal and distal ultrasound-guided approaches are widely utilized for GON RFA. These approaches aim to disrupt pain signals transmitted by the GON and provide relief of pain for these headache disorders

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with combined migraine and cervicogenic headache according to The International Classification of Headache Disorders (ICHD)
  • Age between 18 and 65 years.
  • Willingness to participate and provide informed consent

Exclusion criteria

  • Previous neurosurgical procedures for headache management.
  • Patients with contraindications for the RF technique
  • Pregnancy or lactation
  • History of psychiatric disorders or substance abuse

Treatment and study plan

proximal ultrasound-guided GON radiofrequency ablation

Procedure

proximal GON radiofrequency

distal ultrasound-guided GON radiofrequency ablation

Procedure

distal GON radiofrequency

Primary outcomes

  1. Numerical rating score

    Time frame: baseline and at follow-up visits (2 weeks.1, 2.3, and 6 months)

    0-10 scale, with 0 indicating no pain and 10 indicating the worst possible pain.

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach): Randomized Clinical Trial

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Nov 7, 2023
Registry last updated
Nov 8, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.