Gastro-intestinal Biopotential Recorder by Means of Surface ELEctrodes

Diseases and disorders of the digestive tract affect a large proportion of the world's population. These disorders or diseases degrade patients' quality of life and are costly for healthcare systems. Today, it is difficult to categorize, monitor and/or prognosticate their evolution due to their unknown etiologies, the long duration of the digestion processes and unsuitable (invasive, complex or costly) examinations.

However, electrophysiology holds great promise for the study of these diseases. Indeed, the organs of the digestive tract are made up of longitudinal and circular muscles which contract rhythmically and synchronously to advance the food bolus during digestion, or to cleanse the digestive tract once digestion is complete.

No study has yet demonstrated the feasibility and value of measuring these bio-potentials for Functional Gastro Intestinal Disorders and Inflammatory Bowel Diseases.

That's why a homemade gastro-intestinal biopotentials recorder was developped. The recorder uses surface electrodes placed on the abdomen to record this biopotentials. The investigators hypothesize that surface gastro-intestinal biopotentials differ between a population of healthy volunteers, Crohn's disease patients and FGID patients.

Inclusion criteria

for all participants:

• Person age > 18 years
• Person has been fasting for at least 12 hours
• Person who has received full information on the organization of the research and has not objected to the use of this data.
• Person affiliated to or beneficiary of a social security plan
• Person informed about study organization and having signed the informed consent

Inclusion criteria

for healthy volunteers :

• Person has no history of chronic gastro-intestinal disease
• Person has no acute of gastro-intestinal disease

Inclusion criteria

for Crohn's disease patients without fibrosis :

• Person is already diagnosed with Crohn's disease
• Person has underwent during the last 6 months :
• An MRI showing no fibrosis
• A blood test for C-reactive protein and fecal calprotectine
• A questionnaire to asses the Harvey-Bradshaw Index

Inclusion criteria

for Crohn's disease patients with fibrosis :

• Person is already diagnosed with Crohn's disease
• Person has underwent during the last 6 months :
• An MRI showing fibrosis
• A blood test for C-reactive protein and fecal calprotectine
• A questionnaire to asses the Harvey-Bradshaw Index

Inclusion criteria

for functional gastrointestinal disorders patients :

• Person is already diagnosed with functional gastrointestinal disorders
• Person has underwent an evaluation of the Rome IV criteria

Exclusion criteria

for all participants:

• Person having a pacemaker
• Person suffering from a sensory disorder making insensitive to pain on the skin
• Person suffering from a mental or motor disorders creating uncontroled movements
• Person being allergic to one or more component of the device
• Person being allergic to : soy, dairy food, peanuts, wheat, nuts
• Person having an history of gastro-intestinal surgery
• Person suffering from injury or erythema on the abdominal skin
• Person having a contagious potential (bacterial, fungal or viral)
• Person being in menstruation period
• Person suffering from urinary incontinence
• Minor (not emancipated)
• Person of legal age (subject to a legal protection measure)
• Adult unable to give consent