Skip to main content
OpenTrials
Completed

NCT Number: NCT07557719

Gamified Learning Methods and HPV Knowledge in Nursing Students

This study is a randomized controlled trial (RCT) with a pretest-posttest-follow-up design that compares the effectiveness of gamified teaching methods (Gimkit and educational escape room) with traditional theoretical education in improving undergraduate nursing students' Human Papillomavirus (HPV) knowledge and HPV literacy. Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. These outcomes represent related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Game-Based Learning Communicable Diseases DNA Virus Infections Disease Attributes Educational Intervention Genital Diseases Infections Nursing Education Papillomavirus Infections Pathologic Processes Pathological Conditions, Signs and Symptoms Sexually Transmitted Diseases Sexually Transmitted Diseases, Viral Tumor Virus Infections Urogenital Diseases Virus Diseases

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Aydın Adnan Menderes University

Aydin, Turkey (Türkiye)

About this study

This randomized controlled trial (RCT) with a pretest-posttest-follow-up design evaluated the effectiveness of two gamified teaching strategies in undergraduate nursing education. The study was conducted among third-year nursing students enrolled in the Obstetrics and Gynecology Nursing course at Aydın Adnan Menderes University.

Participants were randomly assigned to one of three groups:

  • Gimkit-based gamification combined with theoretical education
  • Educational escape room combined with theoretical education
  • Control group (theoretical education only)

All participants received standardized theoretical instruction on Human Papillomavirus (HPV). Subsequently, participants in the intervention groups completed either the Gimkit or educational escape room activity, whereas the control group received no additional educational intervention.

Data were collected using the following instruments:

  • Student Information Form
  • Human Papillomavirus (HPV) Knowledge Scale
  • Human Papillomavirus Literacy Scale (HPV-LS)
  • Gameful Experience Scale (GAMEX)

Both HPV knowledge and HPV literacy were prespecified primary outcome measures in the study protocol. HPV knowledge and HPV literacy address related but distinct educational constructs and are reported separately to allow independent interpretation of each outcome.

Data were analyzed using IBM SPSS Statistics version 25.0. Descriptive statistics were calculated for all variables. Baseline continuous variables were compared using one-way analysis of variance (ANOVA), whereas categorical variables were analyzed using the chi-square test or Fisher's exact test, as appropriate. Changes in study outcomes over time were evaluated using two-way repeated-measures ANOVA with Bonferroni-adjusted pairwise comparisons, as appropriate. Statistical significance was set at p < 0.05.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being a third-year undergraduate nursing student enrolled in the Obstetrics and Gynecology Nursing course
  • Voluntary participation
  • Participation in all measurement points
  • Ownership of a smartphone
  • Internet access
  • Having headphones.

Exclusion criteria

Previous experience with Gimkit or educational escape room activities Incomplete data forms Not participating in intervention sessions Absence from the posttest or follow-up assessment

Treatment and study plan

Gimkit-Based Game-Based Learning

Behavioral

Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in a Gimkit-based digital quiz game consisting of multiple-choice and true/false questions designed to reinforce HPV-related knowledge.

Escape Room-Based Game-Based Learning

Behavioral

Participants will receive standardized theoretical education on Human Papillomavirus (HPV), followed by participation in structured escape room-based learning activities consisting of crossword puzzles, word search tasks, and matching exercises designed to reinforce HPV-related knowledge.

Primary outcomes

  1. HPV Knowledge Level

    Time frame: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).

    Human Papillomavirus (HPV) Knowledge Scale. Scores range from 0 to 33; higher scores indicate greater knowledge.

  2. HPV Literacy Level

    Time frame: Baseline (Day 0, before theoretical education; 17 April 2026), immediately after theoretical education (Day 0; 17 April 2026), immediately after the intervention (Day 7; 24 April 2026), and follow-up (Day 28; 15 May 2026).

    Human Papillomavirus (HPV) Literacy Scale. Scores range from 24 to 120; higher scores indicate higher literacy.

Secondary outcomes

  1. Gamified Learning Experience

    Time frame: Immediately after completion of the gamified intervention (Day 7; 24 April 2026).

    Measured using the Gameful Experience Scale (GAMEX). Higher scores indicate a more positive gamified learning experience.

Sponsors and collaborators

Lead sponsor

Aydin Adnan Menderes University

Other

Registry information

Official study title

Effect of Gimkit and Escape Room Teaching Methods on Nursing Students' Knowledge and Literacy Levels Regarding Human Papillomavirus (HPV): A Randomized Controlled Trial

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 29, 2026
Registry last updated
Jul 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.