Flavanol-Rich Cocoa and Cerebral Blood Flow

The purpose of the study is to learn whether or not cocoa has a beneficial effect on blood flow to the brain in older subjects with diabetes mellitus or hypertension (high blood pressure). We hypothesize that cocoa, which contains flavanols (a type of polyphenol), may help to promote blood flow to the brain in older people with diabetes or hypertension.

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Key information

Conditions

Hypertension Cardiovascular Diseases Diabetes Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases Vascular Diseases

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

diabetes and/or hypertension

Exclusion criteria

alzheimers disease, dementia, stroke, recent angina or heart attack

Treatment and study plan

cocoa

Dietary Supplement

two servings of cocoa daily for one month

Other names: Cocoa Pro

Primary outcomes

functional transcranial doppler measures

Time frame: 1 month

Sponsors and collaborators

Lead sponsor

Brigham and Women's Hospital

Other

Collaborators

MasterFoods

Registry information

Official study title

Flavanol-Rich Cocoa, Vascular Responses and Mechanisms

Important dates

Study start: 2009
Primary completion: 2012
Study completion: 2013
First posted: Jan 21, 2009
Registry last updated: Apr 30, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed