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OpenTrials
Completed

NCT Number: NCT03348566

Fish and Marine Fatty Acids, Genetic Signatures of Diet Adaptation, and Long-term Weight Changes

the investigators tested whether genetic variants near FADS cluster, which were recently identified to be signatures of adaptation to fish- and n-3 PUFAs-rich diet, interacted with these dietary factors on long-term change of body mass index (BMI).

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Key information

Conditions

Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 11,323 women of European ancestry.
  • Informed consent was obtained from all participants. The DNA extraction methods, quality control measures,
  • SNPs genotyping and imputation data are available .
  • Both cases and controls with genotyping data are available based on GWASs

Exclusion criteria

  • participants without genetic data

Treatment and study plan

fish

Other

fish intkae

Primary outcomes

  1. weight changes

    Time frame: 6-10 years

    long term weight changes: this study measured body weight at baseline (1990) and follow up body weight in 2000. The long term body weight was defined as changes from baseline to follow up endpoint

Sponsors and collaborators

Lead sponsor

Harvard School of Public Health (HSPH)

Other

Registry information

Official study title

Fish and Marine Fatty Acids, Genetic Signatures of Diet Adaptation, and Long-term Weight Change

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Nov 21, 2017
Registry last updated
Dec 19, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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