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NCT Number: NCT07264374

Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients by Sonographic Evaluation Before and After Resuscitation.

The aim of this study is to evaluate correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED by sonographic evaluation before and after resuscitation.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Emeregency medicine department ,Assiut University

Asyut, Weledea, Egypt

Location contact

Mahmoud Ahmed Abdelrady Mahmoud, M.B.B.Ch

CONTACT

[email protected]

20+01013174106

About this study

Polytrauma patients often present with hemodynamic instability where rapid and accurate assessment of intravascular volume is crucial. Central venous pressure monitoring, though considered a standard, is invasive and not always feasible in emergency settings. Point-of-care ultrasound (POCUS) provides a non-invasive alternative through assessment of venous collapsibility indices.

The inferior vena cava (IVC) collapsibility index is commonly used, but its evaluation may be limited in cases of abdominal trauma, obesity, or technical difficulties. The internal jugular vein (IJV) and femoral vein (FV) are superficial, easily accessible, and may provide reliable alternatives.

This study aims to compare the collapsibility indices of the IVC, IJV, and FV in polytrauma patients before and after resuscitation using sonographic evaluation. The objective is to determine their relative accuracy and feasibility as non-invasive markers of intravascular volume status to guide resuscitation in emergency settings.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients aged ≥ 18years. ( Patients presented by hypovolemic shock

Exclusion criteria

  • Patient refusal Body Mass Index > 40 kg/m2. Cardiac patients or cardiac tamponade Aortic injury or for cardio-thoracic emergent operation Patients with abdominal mass or other pathology as abdominal collection. Any patient needs emergent surgical intervention History of pulmonary artery hypertension. Femoral vein occlusion. Pregnancy. Pulmonary oedema. Patients will need mechanical ventilation.

Treatment and study plan

Ultrasound assesment of FV,IJV and IVC collabsibillity indecis

Device

Ultrasound-Guided Inferior Vena Cava,femoral vein and internal jugular vein collabsibilty indecis Assessment This intervention involves bedside ultrasound measurement of the inferior vena cava (IVC) diameter and calculation of the IVC collapsibility/distensibility index. Assessments will be performed both at initial presentation and after fluid resuscitation in shock patients. The procedure is non-invasive, rapid, and performed according to standardized emergency ultrasound protocols.

Primary outcomes

  1. correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED before and after resuscitation.

    Time frame: correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients at time of presentation to the ED and after one hour of resuscitation.

Study contacts

Contact information is provided by the study sponsor or research team.

Adel Hamid Elbaih, Professor

CONTACT

[email protected]

20+201104534669

Mahmoud Ahmed Abdelrady Mahmoud, M.B.B.Ch

CONTACT

[email protected]

20+01013174106

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Comparative Study of Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients Presenting to the Emergency Department by Sonographic Evaluation Before and After Resuscitation.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 4, 2025
Registry last updated
Dec 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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